Ultra-wide field fluorescein angiography (UWFFA) is a new technique emerging in recent years.UWFFA can observe the fluorescence signs of wide areas of retina beyond the traditional 7-field of vision.UWFFA has obvious advantages in peripheral retina of vascular diseases, such as diabetic retinopathy (DR) , retinal vein occlusion (RVO) and familial exudative retinopathy.Traditional fundus fluorescein angiography (FFA) has accumulated much experience in normal fluorescence and abnormal fluorescence, but little is known about the fluorescence characteristics of normal eye periphery.Periphery fluorescence performance is different from posterior pole and equator.It is necessary to consider the distribution of retinal pigment epithelium (RPE) , pigmentation, vascular development and posterior vitreous cortex.At the same time, more attention should be paid to the influence of age and systemic metabolic diseases on some fluorescence.Light performance also needs dynamic whole-course analysis, combined with color fundus photography and anterior endoscopy analysis.Defining normal fluorescence of different parts of retina at different times is the premise of judging abnormal fluorescence.In clinic, it is necessary to carefully interpret the peripheral fluorescence signs of UWFFA, especially in diagnosis of vascular diseases, such as RVO and DR.It is essential to continuously accumulate experience in interpreting fluorescence signs of normal and abnormal peripheral retina, and further improve the application of UWFFA technology.