Clinical Sciences
Stability of anterior chamber after implantable collamer lens V4c implantation for one year in moderate and high myopic eyes
Lei Cheng, Ran Zhu, Chao Song, Ping Yuan, Yue Tan, Mei Wei
Published 2021-12-10
Cite as Chin J Exp Ophthalmol, 2021, 39(12): 1059-1064. DOI: 10.3760/cma.j.cn115989-20190413-00180
Abstract
ObjectiveTo investigate the stability of anterior chamber following implantable collamer lens (ICL) V4c implantation for one year in moderate and high myopic eyes.
MethodsAn observational case series study was conducted.Medical data of 19 patients (37 eyes) who received ICL V4c implantation in Xuzhou First People's Hospital from March 2016 to October 2017 were collected.The patients were 20 to 29 years old, with the preoperative spherical equivalent (SE) of -5.875 to -15.750 D, with an average of (-9.743±3.220)D.All eyes were followed up for one year, and the changes of visual acuity, SE and intraocular pressure were observed.Pentacam anterior eye segment analyzer was used to measure the anterior chamber depth (ACD), anterior chamber volume (ACV) and anterior chamber angle (ACA) before operation and at 1 month, 6 months and 1 year after operation, and to evaluate the vaults of the ICL V4c at different time points after implantation.This study protocol adhered to the Declaration of Helsinki and was approved by an Ethics Committee of Xuzhou First People's Hospital (No.xxy11[2015]-XJS-004). Written informed consent was obtained from each subject.
ResultsThere were statistically significant differences in visual acuity between before and after operation (F=5.057, P=0.007), and the one-year postoperative uncorrected visual acuity (UCVA) was significantly better than the best corrected visual acuity (BCVA) before operation (P<0.05). There were no significant differences in SE and intraocular pressure among different time points (F=1.294, 1.302; both at P>0.05). There were significant differences in ACD, ACV and ACA among different time points (F=44.811, 889.971, 196.096; all at P<0.001). ACD, ACV and ACA at 1 month, 6 months and 1 year after operation were significantly lower than those before operation (all at P<0.001). There was a significant difference in the 1-month, 6-month and 1-year postoperative ICL vault (F=7.256, P=0.001). The ICL vault at 1 year after operation was (433.784±168.550)μm, which was significantly decreased in comparison with (484.860±183.634)μm at 1 month and (464.351±170.167)μm at 6 months after operation (P=0.006, 0.041).
ConclusionsThe anterior chamber is stable in one year after ICL V4c implantation, and the UCVA is better than preoperative BCVA.ICL V4c is safe and effective for moderate and high myopia.
Key words:
Myopia; Biometry; Anterior chamber/structure; Implantable collamer lens; Pentacam anterior segment analyzer
Contributor Information
Lei Cheng
Department of Ophthalmology, Xuzhou First People's Hospital, Xuzhou Eye Institute, Xuzhou 221002, China
Ran Zhu
Department of Ophthalmology, Xuzhou First People's Hospital, Xuzhou Eye Institute, Xuzhou 221002, China
Chao Song
Department of Ophthalmology, Xuzhou First People's Hospital, Xuzhou Eye Institute, Xuzhou 221002, China
Ping Yuan
Department of Ophthalmology, Xuzhou First People's Hospital, Xuzhou Eye Institute, Xuzhou 221002, China
Yue Tan
Department of Ophthalmology, Xuzhou First People's Hospital, Xuzhou Eye Institute, Xuzhou 221002, China
Mei Wei
Department of Ophthalmology, Xuzhou First People's Hospital, Xuzhou Eye Institute, Xuzhou 221002, China
