The current problems in the textbook of pharmacology for pharmacy majors were analyzed and several suggestions were proposed：modifying the current textbook; inviting senior clini-cal experts to act as the consultants and editorial board members for the textbooks; coping with the disconnection between the clinical medication and theoretical teaching; deleting the obsolescence in the textbook and adding the fresh ideas when teaching; compiling the supplementary materials for the textbook of pharmacology. All these measures made the textbook more informative, practicable, inter-esting and instructive and highlighted the characteristic of pharmacy. Meanwhile, this reform on the textbook broadened the students＇ horizon, triggered students＇ learning interests, cultivated students＇ innovative thinking ability and promoted the quality of pharmaceutical talent.