Clinical Researches
A retrospective study of analysis of risk factors of postoperative acute kidney injury in acute Stanford type A aortic dissection
Shi Haipeng, Wang Xiuzhe, Yang Xiaojing, Xia Yanmei, Wu Weidong, Wu wenjing, Yang Lingbo
Published 2017-11-28
Cite as Chin J Crit Care Intensive Care Med, 2017,3(4): 275-279. DOI: 10.3877/cma.j.issn.2096-1537.2017.04.009
Abstract
ObjectiveTo determine the risk factors of acute kidney injury (AKI) following type Stanford A Aortic Dissection (AD) operation.
MethodsWe retrospectively analyzed the clinical data of 78 patients with Stanford A AD who underwent operation from Jun 2012 though Dec 2016. The patients were divided into AKI and non-AKI groups according to the KDIGO definition 2012. The risk factors of AKI were evaluated by comparing the clinical data of two groups.
ResultsOf all included patients, 45(57.7%) patients developed to AKI and 36(46.2%) patients received renal replacement therapy (RRT). The hospital mortality was 7.7%. Univariate analysis revealed that preoperative creatinine (t=16.395, P<0.001), cardiopulmonary bypasstime (t=2.274, P=0.026), deep hypothermic circulatory arrest time (t=3.278, P=0.002), blood transfusion during operation (t=16.448, P<0.001), operation time (t=3.703, P<0.001), oxygenation index≤100 mmHg (t=11.341, P<0.001) postoperation were risk factors of AKI. Multivariate logistic analysis showed that preoperative creatinine(OR=11.364, 95%CI: 1.363~8.258, P=0.032) and oxygenation index≤100 mmHg (OR=15.263, 95%CI: 1.152~7.382, P=0.043) following-operation were independent risk factors for AKI.
ConclusionElevated preoperative creatinine level and oxygenation index≤100 mmHg following operation were independent risk factors of AKI in acute type A dissection surgery patients.
Key words:
Dissection of aorta; Complication; Acute kidney injury; Risk factors
Contributor Information
Shi Haipeng
Department of Critical Care Medicine, ShanXi DaYi Hospital, Taiyuan 030032, China
Wang Xiuzhe
Department of Critical Care Medicine, ShanXi DaYi Hospital, Taiyuan 030032, China
Yang Xiaojing
Department of Critical Care Medicine, ShanXi DaYi Hospital, Taiyuan 030032, China
Xia Yanmei
Department of Critical Care Medicine, ShanXi DaYi Hospital, Taiyuan 030032, China
Wu Weidong
Department of Critical Care Medicine, ShanXi DaYi Hospital, Taiyuan 030032, China
Wu wenjing
Department of Critical Care Medicine, ShanXi DaYi Hospital, Taiyuan 030032, China
Yang Lingbo
Department of Cardiac surgery , ShanXi DaYi Hospital, Taiyuan 030032, China