Original Article
Fiberoptic ductoscopy and O3 treatment for plasma cell mastitis with nipple discharge and lumps
Jinjuan Peng, Yunsuo Zhang, Hui Yang, Xiaoyan Zou, Lili Fan, Huamao Chi
Published 2019-08-01
Cite as Chin J Breast Dis(Electronic Edition), 2019, 13(4): 202-206. DOI: 10.3877/cma.j.issn.1674-0807.2019.04.003
Abstract
ObjectiveTo investigate the therapeutical effect of fiberoptic ductoscopy and O3 treatment for plasma cell mastitis (PCM) with nipple discharge and lumps.
MethodsTotally 50 PCM patients with nipple discharge and lumps in the Fourth People’s Hospital of Zhenjiang from December 2013 to February 2016 were enrolled for a prospective study. By flipping the coin, they were randomly divided into two groups: one group receiving fiberoptic ductoscopy combined with O3 treatment (n=25) and the other group receiving conventional treatment (n=25). The Mann-Whitney U test and χ2 test were used to compare the therapeutical effect, duration and cost of therapy between two groups.
ResultsOn the third day of the treatment, the lump was significantly reduced in fiberoptic ductoscopy group compared with conventional treatment group [volume reduction: 40.0(25.3-51.1)% vs 16.7(8.9-28.8)%, Z=-3.800, P< 0.001] and the numerical rating scale (NRS) scores for pain was significantly lower in fiberoptic ductoscopy group than that in conventional treatment group [3.0(2.0-4.0) vs (5.0-6.0), Z=-2.717, P=0.007]. The fiberoptic ductoscopy group showed a significantly higher effective rate [92%(23/25) vs 68% (17/25), χ2=4.500, P= 0.034] and shorter duration [9.0 (7.0-12.5) d vs 18.0(14.0-24.5) d, Z=-4.308, P<0.001) compared with conventional treatment group, but there was no significant difference in cost of therapy [2 947.0(2 406.0-3 517.5) RMB vs 3 033.0(2 515.5-4 839.5) RMB, Z=-0.611, P=0.541].
ConclusionFiberoptic ductoscopy and O3 treatment for plasma cell mastitis with nipple discharge and lumps are clinically feasible, which can quickly reduce the lump size, relieve the pain, decrease the treatment duration and increase the effective rate, without increasing the cost of therapy.
Key words:
Mastitis; Ozone; Galactorrhea; Endoscopy
Contributor Information
Jinjuan Peng
Department of Breast Surgery, Fourth People’s Hospital of Zhenjiang, Zhenjiang 212001, Jiangsu Province, China
Yunsuo Zhang
Hui Yang
Xiaoyan Zou
Lili Fan
Huamao Chi