Clinical Researches
Multi-center study of blood lipids in younger patients with hypertensive cerebral hemorrhage
Yuan Chai, Weiping Liu, Panpan Xian, Qiang Luo, Yu Miao, Hujin Zhang, Cairui Fan, Jianzhong Gao, Chenguang Jia, Yang Liu, Menglong Song, Yuqi Zhang, Qianfa Long
Published 2019-04-15
Cite as Chin J Clinicians(Electronic Edition), 2019, 13(8): 572-576. DOI: 10.3877/cma.j.issn.1674-0785.2019.08.003
Abstract
ObjectiveTo explore the characteristics of blood lipids in younger patients with hypertensive intracerebral hemorrhage (HICH).
MethodsWe collected the blood samples from HICH patients in eight hospitals, and then divided them into either a younger patient group (30-40 years old) or an older patient group (50-60 years old). At the same time, younger and older healthy people were randomly selected as control groups. The levels of total cholesterol (TCH), triglyceride (TG), high-density lipoprotein (HDL-C), and low-density lipoprotein (LDL-C) in blood were examined, and their differences were compared between different groups by t-tests.
ResultsThe levels of TG and HDL-C presented a significant difference between the younger patient and healthy groups [(1.95±1.34) mmol/L vs (1.25±0.63) mmol/L, t=5.40, P<0.001; (1.18±0.45) mmol/L vs (1.34±0.36) mmol/L, t=3.23, P=0.001], and TG level in the younger patient group was significantly higher than that of the older patient group [(1.95±1.34) mmol/L vs (1.43±1.09) mmol/L, t=3.39; P=0.001]. However, the level of HDL-C in the younger patients was significantly lower than that in the older HICH patients [(1.18±0.45) mmol/L vs (1.35±0.38) mmol/L, t=3.30; P=0.001]. Besides, 46.5% of younger HICH patients had abnormal TG levels.
ConclusionAbnormal level of TG or HDL-C is an important risk factor for HICH in younger patients, and monitoring and management of blood lipids such as TG is a promising preventive method against HICH in younger people.
Key words:
Younger age; Hypertensive intracerebral hemorrhage; Blood lipids; Triglyceride
Contributor Information
Yuan Chai
Department of Neurosurgery, Minimally Invasive and Translational Medicine Center, Xi′an Central Hospital, Xi′an 710003, China
Weiping Liu
Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi′an 710032, China
Panpan Xian
Department of Neurosurgery, Minimally Invasive and Translational Medicine Center, Xi′an Central Hospital, Xi′an 710003, China
Qiang Luo
Department of Neurosurgery, Minimally Invasive and Translational Medicine Center, Xi′an Central Hospital, Xi′an 710003, China
Yu Miao
Department of Neurosurgery, Minimally Invasive and Translational Medicine Center, Xi′an Central Hospital, Xi′an 710003, China
Hujin Zhang
Department of Neurosurgery, Minimally Invasive and Translational Medicine Center, Xi′an Central Hospital, Xi′an 710003, China
Cairui Fan
Department of Neurosurgery, the 187th Central Hospital of the People's Liberation Army, Haikou 571159, China
Jianzhong Gao
Department of Neurosurgery, Yulin First Hospital, Yulin 718000, China
Chenguang Jia
Department of Neurosurgery, Zhuzhou People's Hospital, Zhuzhou 412008, China
Yang Liu
Department of Neurosurgery, the Third People's Hospital of Mianyang, Mianyang 621000, China
Menglong Song
Department of Emergency, Sichuan Provincial People's Hospital, Chengdu 610072, China
Yuqi Zhang
Department of Neurosurgery, Binzhou People's Hospital, Binzhou 256610, China
Qianfa Long
Department of Neurosurgery, Minimally Invasive and Translational Medicine Center, Xi′an Central Hospital, Xi′an 710003, China
