To study clinical characteristics, outcomes and correlated factors of severe preeclampsia(S-PE) complicating placenta abruption .

A retrospectively study of 428 cases of severe preeclampsia who delivered in the Department of Obstetrics, Second Hospital of Tianjin Medical University from March 1992 to March 2009 was conducted. They were divided into observation group (n=48) and control group (n=380) on account of whether complicated placenta abruption. Informed consent was obtained from all participates. The correlated factors, clinical characteristics and outcomes of placenta abruption between two groups were compared.

①The incidence of severe preeclampsia was 3.28%(48/428), and the incidence of placenta abruption among severe preeclampsia was 11.21%(48/428). ②General information and delivery: There were no significant differences regarding mean age, body mass index (BMI) and gestational weeks between two groups (P>0.05). The C-section rate in observation group (87.5%, 42/48)was higher than that of control group (73.15%, 278/380) (P<0.05). ③Correlated factors and clinical characteristics: There were significant differences in mean diastolic blood pressure, protein-uria in 24 h, low albumin-emia, abdominal water, retinal arteriola hemorrhage and bloody at first trimester between two groups (P<0.05). ④Placenta sites: The placenta at fundus or cornu of uterus were 36/48 vs. 139/380 (P<0.05). ⑤Other complications and outcomes: There were significant differences of disseminated intravascular coagulation (DIC, 11/48 vs. 2/380), hysterectomy (2/48 vs. 0/380), prenatal death (12/48 vs. 35/380) between two groups (P<0.05).

Severe preeclampsia complicating low albumin-emia, abdominal water, placenta site at fundus or cornu of uterus, retinal arteriola hemorrhage and bloody at first trimester maybe correlated with placenta abruption.

severe preeclampsia(S-PE); placenta abruption; perinatology