Thyroid disease is one of prevalent endocrine disease among child-bearing aged women, including preconceptional thyroid disease and thyroid disease during pregnancy. The aim of this paper is to focus on preconception care for preconceptional thyroid disease in child-bearing aged women. Thyroid disease and sub-clinical thyroid disease would cause adverse effect on mother and fetal if their disease were not controlled in stable condition. Evidence showed that medical examination before conception could identify risk factors effecting pregnancy outcome,thus providing counseling and intervention according to the risk factors for them will modify the pregnancy outcomes of women with thyroid disease and prevent for malformed children.

hyperthyroidism; hypothyroidism; preconception counseling; malformed children