Short Research Article
Clinical characteristics of 83 children with severe influenza A
Xu Lin, Zhang Yanlan, Wang Caiying, Pang Lin
Published 2020-02-15
Cite as Chin J Exp Clin Infect Dis (Electronic Edition), 2020,14(01): 69-72. DOI: 10.3877/cma.j.issn.1674-1358.2020.01.012
Abstract
ObjectiveTo investigate the clinical characteristics of severe influenza A in children.
MethodsThe clinical data of 83 children with severe influenza A in Department of Pediatric, Beijing Ditan Hospital, Capital Medical University were collected, the data of sex, age, duration of fever, complications and prognosis were analyzed, retrospectively.
ResultsAmong the 83 children with severe influenza A, 43 cases (51.81%) were male and 40 cases (48.19%) were female, with an average age for (2.43±1.5) years old. All 83 children had fever, with the mean highest peak of fever for (39.72±0.77)℃and the mean fever time was (3.02±2.35) d. There were 51 cases (61.45%) with respiratory system complications, 31 cases (37.35%) with nervous system complications, 23 cases (27.71%) with circulatory system complications, 14 cases (16.87%) with digestive system complications, 29 cases (34.94%) with blood system complications; 15 cases (18.07%) with other complications (electrolyte disturbance). Co-infection: there were 24 cases (28.91%) with bacterial infection, 22 cases (26.50%) with mycoplasma infection, 16 cases (19.28%) with viral infection and 1 case (1.20%) with fungal infection. All 83 children were treated with neuraminidaseinhibitor and symptomatic support therapy, among whom, 2 cases discharged automatically (state improved) and 81 cases were cured and discharged. The average hospitalization days of 83 caese were (5.80±3.12) d,among whom, the average hospitalization days of cases with non-pneumonia was (5.45±2.87) d, while cases with pneumonia were (5.45±2.87) d, and the maximum was 23 d.
ConclusionsSevere influenza A occur mostly in children under 5 years old, especially in children with 3-4 years old, commonly with respiratory complications, cases with pneumonia complications commonly had long hospitalization period, and were susceptible to various or multiple pathogen infection. Severe influenza A had great negative impact on children’s health, but with good prognosis through active treatment. It was necessary to strengthen the understanding of severe influenza A, make early diagnosis and treatment, minimize the harm of disease and improve the rate of early cure.
Key words:
Children; Severe Influenza A; Clinical characteristics
Contributor Information
Xu Lin
Department of Pediatric, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
Zhang Yanlan
Wang Caiying
Pang Lin
