Research Article
Cross-sectional study on knowledge of medical workers towards hepatitis virus screening and monitoring of tuberculosis patients in Yunnan province
Zhan Shuhua, Yang Zhibin, Shu Huiyong, Kuang Chongshu, Li Guolun, Shen Enrui, Ma Wanhong, Ma Shiwu
Published 2020-02-15
Cite as Chin J Exp Clin Infect Dis (Electronic Edition), 2020,14(01): 31-39. DOI: 10.3877/cma.j.issn.1674-1358.2020.01.006
Abstract
ObjectiveTo investigate the knowledge of medical workers towards the screening and management of hepatitis B/C virus (HBV/HCV) among patients with tuberculosis.
MethodsA questionnaire survey was conducted in tertiary and secondary comprehensive hospitals of 16 autonomous prefectures and cities in Yunnan Province in 2018. The participants should be involved in the diagnosis and treatment of tuberculosis, and their decisions on screening and monitoring serum biomarkers of HBV and HCV before anti-tuberculosis and glucocorticoid treatment were collected.
ResultsA total of 1 000 questionnaires were sent out, and 942 questionnaires were collected. After 52 invalid questionnaires were excluded, 890 questionnaires were finally valid, which came from 21 tertiary hospitals and 64 secondary hospitals. The proportion of medical workers deciding to screen anti-HCV (48.8%, 434/890) was significantly lower than that of deciding to screen HBsAg (hepatitis B surface antigen) (70.7%, 629/890;χ2 = 88.805,P < 0.001) before anti-tuberculosis treatment. The proportion of medical workers who decided to screen anti-HCV (72.1%, 642/890) was also lower than that for HBsAg screening (75.6%, 673/890) before glucocorticoid treatment, although the overall difference was not significant (χ2= 2.794, P = 0.094). Binary logistic regression multivariate analysis showed that the department category and professional title were independent predictors for medical workers screening anti-HCV before glucocorticoid treatment. The knowledge of decision on screening anti-HCV were relatively higher among the medical workers in the department of infectious diseases (OR= 1.834, 95%CI: 1.342-2.505,P= 0.001), the senior title (OR= 1.745, 95%CI: 1.115-2.731,P =0.015). Hospital level, department category and professional title were independent predictors for medical workers screening HBsAg before glucocorticoid treatment. The knowledge of decision on screening HBsAg were relatively higher among the medical workers in tertiary hospital (OR= 1.735, 95%CI: 1.223-2.441,P= 0.002), in the department of infectious diseases (OR= 1.567, 95%CI: 1.133-2.167,P = 0.007) and the senior title (OR = 1.786, 95%CI: 1.104-2.888,P = 0.018). During glucocorticoid treatment, both hospital level and department category were independent predictors for medical workers to monitor HCV RNA. The knowledge of decision on monitoring HCV RNA were relatively higher among the medical workers in tertiary hospital (OR= 1.898, 95%CI: 1.285-2.802,P= 0.001), in the department of infectious diseases (OR= 2.039, 95%CI: 1.391-2.988,P < 0.001) than those of staff in secondary hospital and not department of infectious diseases and hospital level, department category and professional title were independent predictors for medical workers to monitor HBV DNA. The knowledge of decision on monitoring HBV DNA were relatively higher among the medical workers in tertiary hospital (OR= 2.019, 95%CI: 1.385-2.943,P < 0.001), in the department of infectious diseases (OR = 2.269, 95%CI: 1.573-3.275,P< 0.001) and the senior title (OR= 2.435, 95%CI: 1.373-4.320,P= 0.002).
ConclusionsMedical workers might have great gaps in their knowledge towards the screening and management of hepatitis virus in tuberculosis patients. Increased training on viral hepatitis to medical worker will benefit prevention of liver injury in tuberculosis patients.
Key words:
Medical workers; Tuberculosis; Hepatitis C virus; Hepatitis B virus; Survey of knowledge
Contributor Information
Zhan Shuhua
Department of Infectious Diseases, the 920th Hospital of the Joint Logistic Support Force of the Chinese People’s Liberation Army, Kunming 650223, China;Department of Postgraduate, Kunming Medical University, Kunming 650500, China;Department of Respiration, Aba Tibetan Autonomous Prefecture People’s Hospital, Maerkang 624000, China
Yang Zhibin
Department of Infectious Diseases, People’s Hospital of Yuxi , Yuxi 653100, China
Shu Huiyong
Department of Infectious Diseases, Dali Bai Autonomous Prefecture People’s Hospital, Dali 671000, China
Kuang Chongshu
Department of Infectious Diseases, People’s Hospital of Lincang, Lincang 677000, China
Li Guolun
Department of Infectious Diseases, People’s Liberation Army the 926 Hospital, Kaiyuan 661600, China
Shen Enrui
Department of Infectious Diseases, People’s Hospital of Jianshui County, Jianshui 654300, China
Ma Wanhong
Department of Infectious Diseases, Dali Bai Autonomous Prefecture People’s Hospital, Dali 671000, China
Ma Shiwu
Department of Infectious Diseases, the 920th Hospital of the Joint Logistic Support Force of the Chinese People’s Liberation Army, Kunming 650223, China;Department of Postgraduate, Kunming Medical University, Kunming 650500, China