Infectious diseases had been evolved from infectious diseases, some of which were contagious. Infectious diseases had a high incidence, many kinds of pathogenic microorganisms and parasites, the whole body of various systems, organs, tissues could be infected with a single or multiple invasion and immune response, and complicated characteristics of the diseases. Infectious diseases had become a global medical problem and a public health problem that affects social stability. In order to solve the problem of clinical prevention and treatment of infectious diseases, the biomedical model was used to limit the thinking to a certain system, organ and tissue, which was not significantly conducive to the scientific diagnosis and treatment of infectious diseases. Under the guidance of the biological-social-psychology model, holistic integrated medicine (HIM) must be applied to clinical diagnosis and treatment. Take the four diseases which need to be focused in China as examples: the diagnosis and treatment of infectious diseases, acute fever, long-term unexplained fever (FUO) and cirrhotic cardiomyopathy (CCM), the necessity and scientific application of HIM in infectious diseases were expound.

Holistic integrative medicine; Infectious medicine; Communicable diseases; Fever of unknown origin; Cirrhotic Cardiomyopathy; Bio-psycho-social medical model