Original Article
Value of intra-aortic balloon pump in ventricular septal rupture after acute myocardial infarction
Xiaoqian Zhou, Xiaoye Ma, Zhiyun Yang, Feng Li, Ying Cai
Published 2018-12-01
Cite as Chin J Crit Care Med(Electronic Edition), 2018, 11(6): 387-392. DOI: 10.3877/cma.j.issn.1674-6880.2018.06.006
Abstract
ObjectiveTo evaluate the value of intra-aortic balloon pump (IABP) in patients with ventricular septal rupture after acute myocardial infarction.
MethodsFrom January 2008 to December 2016, 10 patients with acute myocardial infarction complicated with ventricular septal rupture admitted to the Department of Cardiology, East Hospital Affiliated to Tongji University were selected, which were divided into the IABP group and drug group with 5 cases in each group. Both groups were treated with dopamine, nitroglycerin, furosemide, aspirin, clopidogrel, while patients in the IABP group were implanted with IABP on the basis of drug therapy. The general data, past history, myocardial infarction characteristics, cardiac function, circulation and urine volume were compared between these two groups. Kaplan-Meier curves were used to compare the survival in these two groups.
ResultsThe time of chest pain in the drug group [(153 ± 67) h vs. (34 ± 13) h] was significantly longer than that in the IABP group (t = 1.591, P = 0.023). After treatment, the mean arterial pressure [(76 ± 7) mmHg vs. (66 ± 5) mmHg] and urine volume [(42 ± 15) mL / h vs. (23 ± 8) mL / h] in the IABP group and drug group were significantly different (t = 2.620, 2.551; P = 0.031, 0.034). The survival curve showed that the survival condition of IABP group was significantly better than that of drug group (χ2 = 280.400, P = 0.041).
ConclusionsEarly use of IABP in patients with ventricular septal rupture after acute myocardial infarction can significantly improve their blood pressure and urine volume, stabilize hemodynamics, gain time for operation and thus reduce mortality. It is an important transitional method before operation.
Key words:
Intra-aortic balloon pump; Acute myocardial infarction; Ventricular septum rupture
Contributor Information
Xiaoqian Zhou
Department of Cardiology, East Hospital Affiliated to Tongji University, Shanghai 200123, China
Xiaoye Ma
Zhiyun Yang
Feng Li
Ying Cai