To evaluate the feasibility and preliminary application effect of CT perfusion imaging (CTPI) of the scanner for patients with ischemic stroke by 16-slices of mobile CT scanner.

Six patients with the ischemic stroke identified by CT or MRI scanning were selected in the trial. Firstly, the patient received an injection of 100 mL of non-ionic contrast through elbow vein high-pressure with a speed of 2.3 mL/s. The 16-slices mobile CT was used to scan the head continuously for CTPI imaging in areas of interest. The scanning conditions were with tube voltage 120 kV and tube current 8 mA. The scanning thickness was 1.1 mm and layer spacing was 4.1 mm in the trial. The brain blood flow (CBF), brain blood volume (CBV), contrast agent mean transit time (MTT) and peak to time (TTP) were calculated in the ischemic areas of interest and the corresponding healthy lateral brain by way of advanced imaging processing system of Anythink CT 16 and the algorithm of deconvolution methods.

The results and imaging qualities of continuous dynamic scanning for CTPI with 16-slices mobile CT were in line with clinical diagnostic criteria. CTPI showed that there was no significant difference in CBF (25.226±6.458) mL·100 g^-1·min^-1, CBV (2.756±0.734) mL/100 g, MTT (3.365±1.450) s, TTP (22.314±4.884) s in the ischemic areas of interest, and compared with CBF (29.672±8.879) mL·100 g^-1·min^-1, CBV (3.714±0.401) mL/100 g, MTT (1.730±0.807) s, and TTP (22.424±5.395) s on the healthy side brain (P>0.05).

A new method of 16-slices mobile CT perfusion imaging had been established successfully. The CTPI imaging was high quality and the data was reliable in the stril.

Stroke; Mobile CT; Cerebral perfusion imaging; Cerebral blood flow; Cerebral blood volume