Review
The application of mass spectrometry technology in clinical laboratory
Beibei Zhao, Xuhui She, Weixia Liu, Wei Li, Heng Dong, Xueyi Xuan, Yating Cheng
Published 2018-02-28
Cite as Chin J Clin Lab Mgt (Electronic Edition), 2018, 06(1): 5-9. DOI: 10.3877/cma.j.issn.2095-5820.2018.01.003
Abstract
Mass spectrometry is a highly complicated and the-state-of-the-art technology, which has been successfully used to many areas as a powerful analytical tool. In recent years, an increasing application of mass spectrometry in clinical laboratory can be observed. Due to its high sensitivity, specificity, and multicomponent analysis capacity, mass spectrometry has strong ability to analysis biomarkers existing in complex matrices, thus it can offer much more acute and reliable results for patient care. This article will base on the characteristics of mass spectrometry, giving a whole picture of the development and main applications of mass spectrometry in clinical laboratory. The problems and challenges that the technology is facing and the future trend of application will be mentioned.
Key words:
Mass spectrometry; Sensitivity; Specificity; Clinical laboratory; Application
Contributor Information
Beibei Zhao
Clinical Mass Spectrometry Center, Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou 510005, China
The Kingmed Laboratory of Guangzhou Medical University, Guangzhou 510005, China
Xuhui She
Clinical Mass Spectrometry Center, Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou 510005, China
The Kingmed Laboratory of Guangzhou Medical University, Guangzhou 510005, China
Weixia Liu
Clinical Mass Spectrometry Center, Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou 510005, China
The Kingmed Laboratory of Guangzhou Medical University, Guangzhou 510005, China
Wei Li
Clinical Mass Spectrometry Center, Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou 510005, China
The Kingmed Laboratory of Guangzhou Medical University, Guangzhou 510005, China
Heng Dong
Clinical Mass Spectrometry Center, Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou 510005, China
Xueyi Xuan
Clinical Mass Spectrometry Center, Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou 510005, China
Yating Cheng
Clinical Mass Spectrometry Center, Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou 510005, China
The Kingmed Laboratory of Guangzhou Medical University, Guangzhou 510005, China
