Imaging Diagnostic Studies
Diagnostic accuracy of the second generation dual-source dual-energy CT myocardial perfusion imaging in patients with suspicious myocardial infarction
Ruijuan Han, Kai Sun, Kuncheng Li, Ruiping Zhao, Wenhuan Li, Shuancheng Bai, Junyan Wang, Hongyu Li, Yaojun Lu
Published 2015-08-26
Cite as Chin J Diagnostics(Electronic Edition), 2015, 03(3): 173-178. DOI: 10.3877/cma.j.issn.2095-655X.2015.03.005
Abstract
ObjectivesTo evaluate the diagnostic accuracy of the second generation dual-source dual-energy CT myocardial perfusion imaging in patients with suspicious myocardial infarction.
MethodsFifty-six patients underwent dual-source dual-energy myocardial perfusion imaging, of which forty patients had follow-up results [confirmed by catheter coronary angiography, cardiac troponin I elevation and Electrocardiogram (ECG) changes and evolution of acute myocardial infarction] within 30 days.Catheter coronary angiography and clinical data served as the standard of references.The sensitivity, specificity and positive and negative predictive values of the second generation dual-source dual-energy CT myocardial perfusion in the detection of myocardial infarction were evaluated.The coronary image quality and radiation dose were evaluated.
ResultsDiagnostic accuracy: the sensitivity, specificity and positive and negative predictive values were 95.0%, 97.0%, 86.4% and 98.9%, respectively.Coronary image quality: one patient with non-diagnostic images was due to motion artifacts occurred at the right coronary artery and left circumflex artery; another patient′s vessels were unassessable due to the motion artifacts induced by high heart rate variability; the other patients′ image quality were good.Radiation dose: the average effective radiation dose was (6.1±1.5)mSv.
ConclusionOne-step dual-source dual-energy CT myocardial perfusion scan combined with coronary CTA provide high diagnostic accuracy for detecting myocardial infarction with lower radiation exposure in patients with suspicious myocardial infarction.
Key words:
Tomography, x-ray computed; Myocardial perfusion imaging; Myocardial infarction; Diagnosis
Contributor Information
Ruijuan Han
Department of Translational Medicine Center, Central Hospital of Baotou, Baotou 014040, China
Kai Sun
Department of Translational Medicine Center, Central Hospital of Baotou, Baotou 014040, China
Department of Medical Imaging Research Institute, Central Hospital of Baotou, Baotou 014040, China
Kuncheng Li
Department of Imaging, Xuanwu Hospital, Beijing 100020, China
Ruiping Zhao
Department of Translational Medicine Center, Central Hospital of Baotou, Baotou 014040, China
Wenhuan Li
Department of Imaging, Xuanwu Hospital, Beijing 100020, China
Shuancheng Bai
Department of Anesthesiology, Central Hospital of Baotou, Baotou 014040, China
Junyan Wang
Department of ICU, Central Hospital of Baotou, Baotou 014040, China
Hongyu Li
Department of Translational Medicine Center, Central Hospital of Baotou, Baotou 014040, China
Yaojun Lu
Department of Translational Medicine Center, Central Hospital of Baotou, Baotou 014040, China
±s表示，不同观察者间的一致性检验采用Cohen′s Kappa分析。
