Review
Role of astrocytes in controlling synaptic information in tripartite synapses
Hang Guo, Yaqun Ma, Haihong Li, Li Ma, Yan Lu, Xiaojun Wang, Yulong Ma
Published 2019-06-15
Cite as Chin J Neurotrauma Surg(Electronic Edition), 2019, 05(3): 182-185. DOI: 10.3877/cma.j.issn.2095-9141.2019.03.013
Abstract
Traditionally, brain function is considered to be exclusive to neuronal activity. Recent studies have shown that in addition to the classical "bidirectional" information flow between presynaptic and postsynaptic neurons, astrocytes also participate in the process of information exchange between synaptic neurons, response to synaptic activity, and regulation of synaptic transmission. We review herein astrocytes integrate and process synaptic information and finally regulate synaptic transmission and plasticity through releasing gliotransmitters.
Key words:
Tripartite synapse; Astrocyte; Synaptic transmission; Synaptic plasticity
Contributor Information
Hang Guo
Department of Anesthesiology, The Seventh Medical Center, The PLA General Hospital, Beijing 100700, China
Yaqun Ma
Department of Anesthesiology, The Seventh Medical Center, The PLA General Hospital, Beijing 100700, China
Haihong Li
Department of Anesthesiology, The Seventh Medical Center, The PLA General Hospital, Beijing 100700, China
Li Ma
Department of Anesthesiology, The Seventh Medical Center, The PLA General Hospital, Beijing 100700, China
Yan Lu
Department of Anesthesiology, The Seventh Medical Center, The PLA General Hospital, Beijing 100700, China
Xiaojun Wang
Department of Anesthesiology, The Seventh Medical Center, The PLA General Hospital, Beijing 100700, China
Yulong Ma
Department of Anesthesiology, The First Medical Center, The PLA General Hospital, Beijing 100853, China