Analysis of clinical features in patients with pneumoconiosis complicated with pulmonary emphysema
Li Xin, Dai Weirong, Li Li, Liu Wenfeng, Yang Zhongxing, Xie Lei
Published 2017-11-20
Cite as Chin Ind Hyg Occup Dis, 2017,35(11): 865-867. DOI: 10.3760/cma.j.issn.1001-9391.2017.11.018
Abstract
ObjectiveTo investigate the clinical features of pneumoconiosis complicated with pulmo-nary emphysema.
Methodsselected 868 patients with pneumoconiosis were selected from December 2015 to December 2016 in Hunan occupational disease prevention and treatment hospital. Collected the results of high-resolution spiral CT, arterial blood gas, ECG, pulmonary function and MRC score. The subjects were divided into pneumoconiosis complicated with pulmonary emphysema group and simple pneumoconiosis group accord-ing to the results of HRCT. The smoking, MRC score, pulmonary function, blood gas and complications were compared.
ResultsA total of 868 patients were enrolled in the study. Emphysema 232 people, accounting for 26.73%. The incidence of emphysema in the first phase of pneumoconiosis was 12.69%, and the incidence rate of emphysema in pneumoconiosis was 17.03%, The incidence of three Stage pneumoconiosis was highest, up to 60.76%, the incidence of emphysema increased with the increase of stages of pneumoconiosis (P=0.000) .The smoking index of pneumoconiosis combined with emphysema group was significantly higher than that of simple pneumoconiosis group (P<0.01) . The MRC score of pneumoconiosis complicated with pulmonary em-physema group was higher than that of simple pneumoconiosis group (P=0.000) . In pneumoconiosis complicat-ed with pulmonary emphysema group the FEV1.0%, FVC%, FEV1.0/FVC, DLCO%, oxygen partial pressure were significantly lower than that of simple pneumoconiosis group (P≤0.05) . The combined rate of Bullae of lung in pneumoconiosis complicated with pulmonary emphysema group was higher than that of simple pneumo-coniosis group (P<0.01) .
Conclusionpneumoconiosis stage and smoking. Patients with pneumoconiosis com-plicated with pulmonary emphysema had heavier breathing difficulties, more serious pulmonary function and active endurance, the degree of hypoxia is more serious, and had a higher incidence of complications. The pul-monary function of pneumoconiosis complicated with pulmonary emphysema is not consistent with the typical CPFE.
Key words:
Pneumoconiosis; Emphysema; Pulmonary fibrosis
Contributor Information
Li Xin
Hunan Institute of Occupational Disease Prevention and Treatment
Dai Weirong
Li Li
Liu Wenfeng
Yang Zhongxing
Xie Lei