Objective To assess the clinical value of extracorporeal membrane oxygenation(ECMO)treatment,we analyzed our hospital ECMO patients on admission APACHE Ⅱ score.Methods Twenty-five ECMO patients in our hospital from April 2008 to August 2011 were included and divided into survival group and death group according to the treatment prognosis.The lowest scores of APACHE Ⅱ of both groups were counted respectively,the various monitoring and laboratory tests taken as APACHE Ⅱ scores and compared between the two groups.Results The score of APACHE Ⅱ in 10 patients of survival group was (33.0 ± 2.9)points;Fifteen patients of the death group was (47.3 ± 4.5) points.There were significantly differences in two groups (t =8.896,P ＜ 0.05).According by the Acute Physiology Score of APACHE Ⅱ standard,assessed the relevant clinical indicators rated of the two groups,and results shown that the body temperature ratings for the survival group (1.4 ± 0.8) points,mean arterial pressure (2.4 ± 0.5) points,heart rate (2.2 ± 0.4) points,breathing (1.6 ± 1.0),oxygen partial pressure (2.3 ± 0.5) points,alveolar-arterial oxygen difference (2.1 ± 0.6) points,pH value (1.1 ± 0.7) points,pointspotassium levels (1.8 ± 0.8) points,hyponatremia (2.1 ± 0.9) points,hematocrit was (1.4 ± 1.1) points,Glasgow coma score (7.2 ± 1.0) points; Death group (2.5 ± 0.8),(3.0 ± 0.7),(2.7±0.6),(2.5 ±1.0),(2.8 ±0.9),(3.1 ±0.5),(3.1 ±0.6),(2.7 ±0.6),(2.9 ±0.6),(2.5 ± 1.1),(9.1 ± 1.8) points,the differences between the two groups were statistically significant (P ＜0.05),the acute physiology score is lower in survival group.Conclusion APACHE Ⅱ score can objectively evaluate the the ECMO treatment success rate,as well as the timing of implementation of ECMO rescue and inclusion criteria quantitative indicators.