The diagnostic value of joint inspection of radionuclide salivary gland scintigraphy and antinuclear antibody examination in Sj(o)gren's syndrome patients
Liu Yan, Yang Aimin, Ou Yangyan, Gao Rui, Cheng Hu, Zhang Fenru
Published 2014-07-25
Cite as Int J Radiat Med Nuel Med, 2014,38(04): 219-222. DOI: 10.3760/cma.j.issn.1673-4114.2014.04.003
Abstract
Objective To investigate the diagnosis value of the joint inspection of radionuclide dynamic images of salivary gland and antinuclear antibody examination in Sj(o)gren's syndrome (SS) patients.Methods Radionuclide dynamic images and antinuclear antibody examination were applied in 30 patients who were confirmed as SS clinically.The diagnostic value of these 2 methods in SS was studied retrospectively.The positive rates were calculated according to the classical definitions.Results Out of the 30 SS cases,antinuclear antibody examination detected 19 cases (63.3% of the cohort).The other 11 cases turned out to be false negative.Compared with antinuclear antibody examination,dynamic salivary gland scintigraphy identified 24 SS cases,and the positive rate was 80%.The positive rate of the joint examination were calculated as 100%,significantly higher than that of radionuclide dynamic images of salivarygland(P<0.05),orantinuclearantibodytest(P<0.01).Conclusion Joint inspection of dynamic salivary gland images and antinuclear antibody tests has very important clinical value in SS screening,diagnosing and evaluating of salivary gland dysfunction.
Key words:
Sj(o)gren's syndrome; Antibodies, Antinuclear; Radionuclide imaging; Salivary gland
Contributor Information
Liu Yan
Department of Nuclear Medicine, the First Affiliated Hospital of Xi'an Jiao Tong University Medical School, Xi'an 710061, China
Yang Aimin
Department of Nuclear Medicine, the First Affiliated Hospital of Xi'an Jiao Tong University Medical School, Xi'an 710061, China
Ou Yangyan
Department of Nuclear Medicine, the First Affiliated Hospital of Xi'an Jiao Tong University Medical School, Xi'an 710061, China
Gao Rui
Department of Nuclear Medicine, the First Affiliated Hospital of Xi'an Jiao Tong University Medical School, Xi'an 710061, China
Cheng Hu
Department of Nuclear Medicine, the First Affiliated Hospital of Xi'an Jiao Tong University Medical School, Xi'an 710061, China
Zhang Fenru
Department of Nuclear Medicine, the First Affiliated Hospital of Xi'an Jiao Tong University Medical School, Xi'an 710061, China