Volume Therapy
Accuracy of variation of end-tidal pressure of carbon dioxide in predicting fluid responsiveness in patients undergoing resection of gastrointestinal tumor
Chen Cheng, Gao Ju, Luo Ke, Zhou Luojing, Chen Mengyuan, Huang Tianfeng, Ge Yali
Published 2018-11-20
Cite as Chin J Anesthesiol, 2018,38(11): 1351-1353. DOI: 10.3760/cma.j.issn.0254-1416.2018.11.019
Abstract
ObjectiveTo evaluate the accuracy of variation of the end-tidal pressure of carbon dioxide(△PETCO2)in predicting the fluid responsiveness in patients undergoing resection of gastrointestinal tumor.
MethodsForty-six patients of both sexes, aged 40-64 yr, with body mass index of 20-24 kg/m2, of American Society of Anesthesiologists physical statusⅡ or Ⅲ, undergoing elective resection of gastrointestinal tumor with general anesthesia, were enrolled in the study.When the change in mean arterial pressure was less than 10% within 5 min after anesthesia induction, 250 ml Ringer′s solution was rapidly infused over 10 min via the peripheral vein.Increase in cardiac index after volume expansion≥15% was considered to be a positive response.The receiver operating characteristic curve for △PETCO2 in determining fluid responsiveness was drawn.
ResultsThe results of receiver operating characteristic curve analysis showed that the area under the curve for △PETCO2 in determining fluid responsiveness(95% confidence interval)was 0.826(0.730-0.942, P<0.05), the critical value 21.9%, sensitivity 76.5%, specificity 90.9%.
Conclusion△PETCO2 can accurately predict the fluid responsiveness in patients undergoing resection of gastrointestinal tumor.
Key words:
Carbon dioxide; Partial pressure; Vascular capacitance
Contributor Information
Chen Cheng
Department of Anesthesiology, Second Xiangya Hospital, Central South University, Changsha 410000, China
Gao Ju
Department of Anesthesiology, Clinical Medical School of Yangzhou University(Subei People′s Hospital of Jiangsu Province), Yangzhou 225001, China
Luo Ke
Department of Anesthesiology, Second Xiangya Hospital, Central South University, Changsha 410000, China
Zhou Luojing
Department of Science and Education, Clinical Medical School of Yangzhou University(Subei People′s Hospital of Jiangsu Province), Yangzhou 225001, China
Chen Mengyuan
Department of Anesthesiology, Clinical Medical School of Yangzhou University(Subei People′s Hospital of Jiangsu Province), Yangzhou 225001, China
Huang Tianfeng
Department of Anesthesiology, Clinical Medical School of Yangzhou University(Subei People′s Hospital of Jiangsu Province), Yangzhou 225001, China
Ge Yali
Department of Anesthesiology, Clinical Medical School of Yangzhou University(Subei People′s Hospital of Jiangsu Province), Yangzhou 225001, China
