Characteristics and the value of renal solid lesions' boundary at contrast-enhanced ultrasonography
LIU Long, DU Lian-fang, LI Fan, LU Guang-zhong, YANG Zhao-rui
Published 2011-02-25
Cite as Chin J Ultrasonogr, 2011,20(02): 138-141. DOI: 10.3760/cma.j.issn.1004-4477.2011.02.014
Abstract
Objective To investigate the characteristic and the value of renal solid lesions' boundary at contrast-enhanced ultrasonography(CEUS). Methods The study included 225 patients (124 males, 101 females) with renal 239 solid lesions [133 renal cell carcinoma(RCC) and 106 benign lesions]. The enhanced mode of lesion boundary at CEUS was observed. The histopathologic pseudocapsule of RCCs was analysed.Results Enhanced modes of all lesions' boundary at CEUS were classified as: type Ⅰ , iso-enhanced boundry in whole phase, 82.85 % (198 of 239) ;type Ⅱ , a perilesional annular highly-enhanced signal at early phase,4.18% (10 of 239);type Ⅲ ,perilesional annular highly-enhanced signal in whole phase,9.62% (23 of 239) ;type Ⅳ, perilesional annular highly-enhanced signal in midium and late phase, 1.25 % (3 of 239) ;type Ⅴ ,iso-enhanced boundry in the mdium and late phase with no enhancment at early phase, 2. 09% (5 of 239). The distribution of types Ⅰ , Ⅱ , Ⅲ between groups were significant different( P=0.000, 0.046,0. 000), the type Ⅳ and Ⅴ was not ( P = 0.256,0.068). The distribution of perilesional annular highlyenhanced signal between benign and RCC groups was statistically different (x2=29. 681, P=0.000).Regared it as a diagnostic criteria of RCC,the sensitivity was 26.32% (35/133) ,the specificity was 99.06%(105/106) ,the positive predictive value was 97.22% (35/36),the negative predictive value was 51.72%(105/203) ,and the accuracy was 58.58% (140/239). The perilesional annular highly-enhanced signal was not correlated with the pseudocapsule in pathology ( P = 1. 000). Conclusions The boundary enhancement mode of renal solid lesions at CEUS was divided into five types. The perilesional annular highly-enhanced signal was important in diagnosis of RCC,which was not correlated with the pseudocapsule in pathology.
Key words:
Ultrasonography; Microbubbles; Kidney neoplasms
Contributor Information
LIU Long
Department of Ultrasound, the First People's Hospital of Shanghai Jiaotong University, Shanghai 200080,China
DU Lian-fang
Department of Ultrasound, the First People's Hospital of Shanghai Jiaotong University, Shanghai 200080,China
LI Fan
Department of Ultrasound, the First People's Hospital of Shanghai Jiaotong University, Shanghai 200080,China
LU Guang-zhong
Department of Ultrasound, the First People's Hospital of Shanghai Jiaotong University, Shanghai 200080,China
YANG Zhao-rui
Department of Ultrasound, the First People's Hospital of Shanghai Jiaotong University, Shanghai 200080,China