Detection of hepatic metastases by contrast-enhanced ultrasound compared with conventional ultrasound and contrast-enhanced computed tomography
LIU Wen-ying, YAN Kun, YIN Shan-shan, YANG Wei, FU Ying, WU Jie, CHEN Min-hua
Published 2012-05-25
Cite as Chin J Ultrasonogr, 2012,21(05): 401-404. DOI: 10.3760/cma.j.issn.1004-4477.2012.05.013
Abstract
Objective To evaluate the role of contrast-enhanced ultrasound (CEUS) on the the detection of hepatic metastases in comparison with conventional ultrasonography (US) and contrastenhanced computed tomography (CECT).Methods Ninety-seven patients with hepatic metastases underwent US,CEUS and CECT images.Their detection of hepatic metastases were compared.Results Hepatic metastases showed five enhancement patterns with CEUS,including bolus hyper-enhancement,peripheral rim enhancement,inhomogeneous enhancement with necrosis,hypo-enhancement,isoenhancement with liver parenchyma,all hepatic metastases showed dark defects in portal and delayed phase.The mean number of metastases at CEUS was greater than that of US (2.6±1.9 vs 1.6 ±1.2,P<0.05).The detection of hepatic metastases was 53.4% and 87.1% respectively(P<0.05).CEUS and CECT have no statistically significant difference in the detection of hepatic metastases (P>0.05).Conclusions CEUS can improve detection of hepatic metastases.
Key words:
Ultrasonography; Microbubbles; Liver neoplasms; Neoplasm metastasis
Contributor Information
LIU Wen-ying
Department of Ultrasound, Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University School of Oncology , Beijing Cancer Hospital & Institute,Beijing l00142,China
YAN Kun
Department of Ultrasound, Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University School of Oncology , Beijing Cancer Hospital & Institute,Beijing l00142,China
YIN Shan-shan
Department of Ultrasound, Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University School of Oncology , Beijing Cancer Hospital & Institute,Beijing l00142,China
YANG Wei
Department of Ultrasound, Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University School of Oncology , Beijing Cancer Hospital & Institute,Beijing l00142,China
FU Ying
Department of Ultrasound, Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University School of Oncology , Beijing Cancer Hospital & Institute,Beijing l00142,China
WU Jie
Department of Ultrasound, Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University School of Oncology , Beijing Cancer Hospital & Institute,Beijing l00142,China
CHEN Min-hua
Department of Ultrasound, Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University School of Oncology , Beijing Cancer Hospital & Institute,Beijing l00142,China