Assessment of regional left ventricular systolic function in patients with hypertrophic cardiomyopathy by real-time three-dimensional echocardiography
PEI Min, L(U) Qing, XIE Ming-xing, WANG Xin-fang, YANG Ya-li, SONG Yue, DENG Yao
Published 2013-05-25
Cite as Chin J Ultrasonogr, 2013,22(05): 369-373. DOI: 10.3760/cma.j.issn.1004-4477.2013.05.001
Abstract
Objective To assess regional left ventricular systolic function in patients with hypertrophic cardiomyopathy (HCM) using real-time three-dimensional echocardiography (RT-3DE).Methods Twenty-five patients with HCM which was asymmetric septal hypertrophy,and twenty healthy subjects were enrolled in the study.The apical four-chamber view of left ventricular was acquired by RT-3DE.The left ventricular volume-time curves were analyzed quantitatively with Tomtec 4D LV-Analysis 3.0,and regional end-diastolic volume and end-systolic volume of left ventricular (rEDV,rESV),the time to minimum systolic volume (rESVT),regional stroke volume (rSV),regional ejection fraction (rEF),regional-global ejection fraction (rgEF) and the parameters of left ventricular dyssynchrony were measured.Results In the HCM group,the values of Tmsv16-Dif,Tmsv16-SD,Tmsv16-Dif%,Tmsv16-SD% were significantly lower compared with the control group (P < 0.01),and rEDV,rSV,rEF and rgEF in hypertrophic segments were lower than those in non-thickening and mild-thickening segments (P <0.05).In the control group,there were no significant difference of those parameters among all segments (P >0.05).The values of rEDV,rSV and rgEF in hypertrophic segments decreased in the HCM group (P <0.05),at the basal level,rEF in hypertrophic segments decreased,at the apical level,it increased,but the differences at the mid-ventricular level between the two groups were not significant;the values of rEF and rgEF in non-thickening and mild-thickening segments increased (P <0.05).Conclusions RT-3DE could sensitively detect left ventricular dyssynchrony and accurately assess regional left ventricular volume and function of different segments in patients with HCM.
Key words:
Echocardiography, real-time three-dimensional; Cardiomyopathy, hypertrophic; Ventricular function, left
Contributor Information
PEI Min
Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology ,Wuhan 430022,China
L(U) Qing
Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology ,Wuhan 430022,China
XIE Ming-xing
Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology ,Wuhan 430022,China
WANG Xin-fang
Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology ,Wuhan 430022,China
YANG Ya-li
Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology ,Wuhan 430022,China
SONG Yue
Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology ,Wuhan 430022,China
DENG Yao
Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology ,Wuhan 430022,China