Relationship of three-dimensional power Doppler ultrasonographic parameters and endocrine profile in different symptoms of patients with polycystic ovary syndrome
Dai Beibei, Ren Yunyun, Sun Li, Kong Fanbin, Qiu Dong
Published 2014-07-25
Cite as Chin J Ultrasonogr, 2014,23(07): 609-613. DOI: 10.3760/cma.j.issn.1004-4477.2014.07.018
Abstract
Objective To study the relationship of three-dimensional power Doppler ultrasonographic parameters and endocrine profile in different symptoms of patients with polycystic ovary syndrome(PCOS).Methods One hundred and forty nine women with PCOS were divided into two groups,which included obese PCOS(OB-PCOS) group and non-obese PCOS (NOB-PCOS) group.The ultrasonic parameters such as follicle number,ovarian average diameter,ovarian volume,stromal volume,follicle volume,vascularization index(Ⅵ),flow index(FI),vascularization flow index(VFI) were measured and compared.Serum levels of luteinizing hormone (LH),follicle stimulating hormone (FSH),progesterone (P),estradiol (E2),testosterone(T),prolactin (PRL),sex hormone binding globulin (SHBG),free androgen index (FAI),fasting plasma glucose (FPG),fasting insulin (FINS),homeostasis model assessment-IR(HOMA-IR) were also measured and compared.The correlation of the ultrasonic parameters and hormonal factors were analyzed.Results The follicle number,ovarian average diameter,ovarian volume,stromal volume,follicle volume,FI and VFI,FINS,HOMA-IR,FAI of OB-PCOS were significantly higher than those of NOB-PCOS (P <0.01 or 0.05),the FSH,SHBG were significantly lower than those of NOB-PCOS (P <0.05 or 0.01).In OB-PCOS group,the follicle number was significantly associated with FSH(r =0.771,P <0.01).The ovarian volume,stromal volume,FI and VFI were significantly associated with HOMA-IR(r =0.412,0.842,0.389,0.415,P <0.05 or 0.01),FI was significantly associated with FAI (r =0.812,P <0.01).In NOB-PCOS group,the follicle number,ovarian volume were significantly associated with FAI(r =0.472,0.552,P <0.05)..Conclusions There are some different characters in ultrasonography and endocrine parameters between obese and non-obese PCOS patients.
Key words:
Ultrasonography; Polycystic ovary syndrome ; Obesity ; Endocrinology
Contributor Information
Dai Beibei
Department of Ultrasound ,Obstetrics and Gynecolgy Hospital of Fudan University, Shanghai 200011 ,China
Ren Yunyun
Department of Ultrasound ,Obstetrics and Gynecolgy Hospital of Fudan University, Shanghai 200011 ,China
Sun Li
Department of Ultrasound ,Obstetrics and Gynecolgy Hospital of Fudan University, Shanghai 200011 ,China
Kong Fanbin
Department of Ultrasound ,Obstetrics and Gynecolgy Hospital of Fudan University, Shanghai 200011 ,China
Qiu Dong
Department of Ultrasound ,Obstetrics and Gynecolgy Hospital of Fudan University, Shanghai 200011 ,China