Objective To discuss the clinical and pathology characters of endobronchial hamartoma and bronchoscopic treatment with thermal ablation and cryotherapy.Methods Three cases of endobronchial hamartoma resected by bronchoscope and diagnosed by pathology during 2010-2012 were collected,the clinical and pathology characters of endobronchial hamartoma and bronchoscopic treatment were discussed.Results The endobronchial tumor was resected completely under the bronchoscope.Pathology of the tumor was hamartoma.The airway was completely opening after the treatment,there was no serious postoperative complications and recurrence during follow up.Conclusions Endobronchial hamartoma is common in adults,imaging with pulmonary lobe/segments distal bronchus soft tissue shadows along with inflammation and atelectasis.It is difficult to diagnose by conventional bronchoscope biopsy because it is too little,it need to take a chunk of tumor for pathological diagnosis.The bronchoscopic treatment with thermal ablation and cryotherapy can remove tumors quickly,and avoid the scar stricture at the same time,so it is effective.