Original Article
Effect and prognostic factors of stereotactic body radiotherapy in patients with early non-small cell lung cancer
Fu Jinping, Jin Fa, Zhang Xiuwei, Chen Hui
Published 2019-12-05
Cite as Int J Respir, 2019,39(23): 1761-1765. DOI: 10.3760/cma.j.issn.1673-436X.2019.23.001
Abstract
ObjectiveTo investigate the efficacy and prognostic factors of stereotactic body radiotherapy (SBRT) in patients with early non-small cell lung cancer (NSCLC).
MethodsSelected hospitalized in our department, a total of 98 patients with non-small cell lung cancer, according to admission order and odd number is divided into control group and SBRT group, control group given conventional radiotherapy, SBRT group given radiotherapy, short-term efficacy and 5-year cumulative survival rates were compared between the two groups after radiotherapy, and use the logistic multifactor analysis the relevant factors that affect survival.
ResultsAfter radiotherapy, the curative effect of SBRT group was better than that of control group (χ2=10.060, P=0.002). Multivariate analysis showed that age, tumor diameter, and treatment were independent influencing factors for survival.
ConclusionsCompared to conventional radiotherapy, SBRT has better short-term efficacy and significantly improves the 5-year cumulative survival rate of patients with NSCLC.Age, tumor diameter, and treatment were associated with 5-year survival.Therefore, early prevention and intervention measures should be taken for patients with these high-risk factors.
Key words:
Carcinoma, non-small-cell lung; Treatment outcome; Prognostic; Stereotactic body radiation; Survival rate
Contributor Information
Fu Jinping
Department of Radiotherapy, the Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China
Jin Fa
Department of Respiratory Medicine, the Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China
Zhang Xiuwei
Department of Respiratory Medicine, the Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China
Chen Hui
Department of Radiotherapy, the Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China
