Clinical Research
Clinical characteristics analysis and literature review of 55 cases with panniculitis
Hui Zheng, Rong Li, Guozhu Che, Liyun Zhang, Huiqin Hao
Published 2019-06-15
Cite as Chin J Rheumatol, 2019, 23(6): 378-381. DOI: 10.3760/cma.j.issn.1007-7480.2019.06.004
Abstract
ObjectiveTo improve the clinical understanding of the disease by retrospective analysing 55 cases of patients with panniculitis.
MethodsThe hospitalized patients with panniculitis were collected from December 2011 to October 2018 in the Shanxi Dayi Hospital Affiliated to Shanxi Medical University. The demographics, clinical manifestations, laboratory examinations and treatments were analyzed and summarized, rate or composition ratio were applied for statistical description of the counting data.
ResultsThe proportion of males and females in the 55 patients was 1∶2.23, with an average of (53±15) years (18-82 years). A total of 52 cases of nodular panniculitis (including 14 cases of mesenteric involvement) and 3 cases of special type of panniculitis were collected. Patients with nodular panniculitis were often presented with subcutaneous nodules or masses. According to the affected parts, they cowld be divided into skin sub-type and systemic sub-type. Among them, 32 cases were skin sub-type and 20 cases are systemic sub-type. The most frequently involved organs were mesenteric and kidney involvement. Nine of 55 patients was complicated with tumor. Patients with mesenteric panniculitis mainly presented with abdominal pain and bloating, which were mainly diagnosed according to CT findings. Patients with systemic panniculitis could be significantly relieved after treatment with coricosteroids and immunosuppressive agents.
ConclusionPanniculitis is an inflammatory disease of unknown etiology. It is frequent in middle-aged and elderly people. It presents with various clinical manifestations and lacks specificity. The diagnosis is mainly based on pathological results. It is easy to be complicated with tumors. When subcutaneous nodules are found, pathological examination should be performed in order to avoid misdiagnosis.
Key words:
Panniculitis; Panniculitis, nodular nonsuppurative; Panniculitis, peritoneal
Contributor Information
Hui Zheng
Department of Rheumatology and Immunology, Shanxi Dayi Hospital affiliated to Shanxi Medical University, Taiyuan 030001, China
Rong Li
Department of Rheumatology and Immunology, Shanxi Dayi Hospital affiliated to Shanxi Medical University, Taiyuan 030001, China
Guozhu Che
Department of Rheumatology and Immunology, Shanxi Dayi Hosptial, Taiyuan 030032, China
Liyun Zhang
Department of Rheumatology and Immunology, Shanxi Dayi Hosptial, Taiyuan 030032, China
Huiqin Hao
Shanxi University of Traditional Chinese Medicine, Jinzhong 030619, China