Objective To investigate postoperative visual rehabilitation and the safety of the operation in aphakia after secondary ARTISAN iris claw intraocular lens anterior chamber implantation.Methods A retrospective analysis of 9 cases (9 aphakic eyes) accepted ARTISAN iris claw intraocular lens anterior chamber implantation was documented.Their eyesight,intraocular pressure,corneal endothelial cell count,equivalent spherical,surgically induced astigmatism (SIA) and postoperative complications were analyzed.Results After 8-20 months (mean 15.3 months) follow-up,all cases postoperative uncorrected visual acuity significantly improved (preoperative 0.05±0.03,postoperative 0.32±0.19,t =4.63,P=0.0017).The best-corrected visual acuity had no significant change (preoperative 0.41±0.29,postoperative 0.58±0.27,t=1.53,P=0.1652).Mean postoperative spheric equivalent at the last visit was 0.96±1.54D,and differ from the target spheric equivalent ±2.0D.The SIA at the last visit was 2.11±0.56D.Mean postoperative endothelial cell density (ECD) was 1423.67±517.15 cell/mm2,preoperative ECD was 1560.89±552.41 cell/mm2,(t =2.79,P =0.0237).Mean endothelial cell density loss at the last visit was 10.9％.Except one case had transient anterior chamber effusion reaction within one week after operation and one case happened the dislocation of the loop after operation,all cases had no obvious postoperative complications.Conclusions Secondary ARTISAN iris claw intraocular lens implantation is clinically safe and effective to correct aphakic eyes which lack of enough capsule support or exist suspensory ligament of lens disruption,though exist surgically induced astigmatism (SIA) in some cases.