Objective To analyze the myopia progression and axial length growth in high myopic children above the age of 6 after oral delivery anthocyanoside for 12 months.Methods Retrospective collection for January 2009 January 2012 in our hospital under the age of 6,10 cases (20 eyes) were included,4 males and 6 females,eyes dilated by atropine eye ointment,there were 5 eyes of spherical equivalent degree-4D-6D,5 eyes of-6D-8D,and 6 eyes of-8D-10D,4 eyes with more than-10D.The optometry degree,axial length,comeal curvature which measured by the Zeiss IOL-Master 6 were self-comparative analyzed after oral delivery anthocyanoside before and after 6 to 12 months.Results The speed of progression of myopia was found slowed down after orally delivery anthocyanoside.The axial growth was slow,more over the axial shortening phenomenon in the high myopia eye were found,but with no significant statistically differences.Amblyopia correction significantly improved after delivery anthocyanoside for 12 months.Conclusions The resuits show that oral delivery anthocyanoside of long-term in children with high myopia can be significantly reduced axial growth and inhibit the myopia progress.It's a usefully way to treat the amblyopia with high myopia patients.