During the development of tumors, interaction and editing occur between immune system and tumor cells. Tumor cells could be eradicated or tumor developments could be inhibited because of the surveillance role of immune system, while immune escape may occur for tumor cells remodeled by immune system. Tumors can induce innate and adaptive immune responses as well alter the anti-tumor effect of the immune system. This re-view will summarizes the development of researches in cancer immunoediting in order to insights references for tumor therapy.