Objective To explore the epidemiological situation of drinking brick-tea fluorosis in Qinhai Province.Methods According to the survey results of drinking brick-tea fluorosis in Qinghai Province in 2006,an investigation was carried out inchildren aged 8-12 in 28 counties of Qinghai Province by the method of field epidemiology in 2010.In the 28 counties,three townships and one town were selected in each county; a primary school was selected in each township (town).Fluoride content of water,brick-tea and urine was determined by using a fluoride ion-selective electrode; dental fluorosis was diagnosed by Deans method.Results In 28 counties of Qinghai Province,the mean of water fluoride concentration was 0.26 mg/L and the rang was 0-1.00 mg/L; the mean of brick-tea fluoride concentration was 1.96 mg/L and the rang was 0.14-12.59 mg/L.Chidren's geometric mean of urinary fluorine concentration was 1.14 mg/L and the rang was 0.03-9.84 mg/L; the average amount of brick-tea water drank daily by each child was (587.09 ± 237.02)ml and the rang was 0-7 000 ml; children's daily fluoride intake from brick-tea was 1.15 mg and the rang was 0-13.65 mg.Chidren's detection rate of dental fluorosis was 24.38％(3 012/12 355),and the index of dental fluorosis was 0.44.Conclusions Drinking brick-tea fluorosis of children aged 8-12 in Qinghai Province has a epidemic trend.Although the state of the disease is not serious,it is widely distributed.The intake from brick-tea water has showed an increasing trend with increasing age,we should strengthen monitoring.