To investigate the epidemic situation of drinking brick- tea fluorosis in Hainan Prefecture, and to provide a scientific basis for making appropriate prevention and control measures.

We carried out an investigation in four countries, Gonghe, Tongde, Guinan and Xinghai, 3 townships and 1 town in each county were selected, and 2 villages were selected from each townships. Dental fluorosis of children aged 8 to 12 was examined, and their urine samples were collected, urine fluorine content was determined at each site; the situation of the dental fluorosis and the skeletal fluorosis of adults over 16 years old were examined, and their urine samples were collected, urine fluorine content was determined at each site; the samples of brick- tea water and the samples of drinking water were collected from the residents of each sits, and fluoride contents was detected. Dental fluorosis was determined by Dean method according to the "Diagnostic Criteria of Dental Fluorosis" (WS/T 208- 2011); skeletal fluorosis was determined by "Diagnostic Criteria of Endemic Skeletal Fluorosis" (WS 192- 1999); the content of urinary fluorine was determined by "Determination of Fluoride in Urine-Ion Selective Electrode Method" (WS/T 89- 1996); the content of water fluoride and tea water fluorine were determined by fluoride ion selective electrode method.

①Children dental fluorosis and the mean of urinary fluoride: A total of 1 824 children aged 8 to 12 were examined, 238 cases were dental fluorosis, the rate of dental fluorosis was 13.05% (238/1 824), and the index of dental fluorosis was 0.27; 1 824 urine samples of children were determined and geometric mean of urinary fluorine was 1.02 mg/L, the range was 0.09- 5.77 mg/L. ②Adult dental fluorosis, clinical skeletal fluorosis and the mean of urinary fluoride: a sum of 1 384 adults were examined, 266 cases of dental fluorosis were detected, the rate of dental fluorosis was 19.22% (266/1 384), and the index of dental fluorosis was 0.45, clinical examination of skeletal fluorosis found degree Ⅰ patient 1 case, degree Ⅱ 3 cases and degree Ⅲ 1 case, and the rate of skeletal fluorosis was 0.36% (5/1 384); 1 384 adult urine samples were tested, and the geometric mean of urinary fluorine was 1.15 mg/L, the range was 0.12 - 7.80 mg/L. ③Fluoride concentration of the water and tea: 1 384 water samples were tested, the mean of fluoride was 0.31 mg/L, the range was 0.20- 0.70 mg/L; 379 tea samples were tested, the mean of fluoride was 2.01 mg/L, the range was 0.23- 12.59 mg/L.

The situation of drinking brick-tea fluorosis is lighter in Hainan, we should pay close attention to the disease, and strengthen the health education.

Tea; Fluoride; Fuorosis, dental; Skeletal fluorosis