CLINICAL ORIGINAL ARTICLE
Relationship between thyroid function and serum vitamin D levels in type 2 diabetic patients
Jia Liu, Yuan Xu, Zhiwei Ning, Li Miao, Yanjin Hu, Guang Wang
Published 2015-03-25
Cite as Chin J Endocrinol Metab, 2015, 31(3): 245-248. DOI: 10.3760/cma.j.issn.1000-6699.2015.03.012
Abstract
A total of 180 type 2 diabetic patients with negative anti-thyroid autoantibodies were recruited. According to the levels of serum 25-OH vitamin D [25(OH)D], these patients were divided into four groups: sufficient group(≥30 ng/ml), insufficient group(20-<30 ng/ml), deficiency group(10-<20 ng/ml), and severe deficiency group(<10 ng/ml). The results showed that compared with sufficient vitamin D group, the group with severe deficient vitamin D had higher TT3, FT3, FT3/FT4, and TSH(all P<0.05). The serum 25(OH)D level was negatively correlated with TSH values(r=-0.207, P<0.05)after adjustment for gender, age, and body mass index. Multivariate regression analysis indicated that serum 25(OH)D level was an independent influencing factor for TSH value(β=-0.201, P<0.05), suggesting that serum 25(OH)D level seems to be correlated with thyroid function in type 2 diabetic patients. (Chin J Endocrinol Metab, 2015, 31: 245-248)
Key words:
Vitamin D deficiency; Diabetes mellitus, type 2; Thyroid function
Contributor Information
Jia Liu
Department of Endocrinology, Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing 100020, China
Yuan Xu
Zhiwei Ning
Li Miao
Yanjin Hu
Guang Wang