Objective To study the focus of future investment measures to be strengthened for schistosomiasis control so as to provide a reference for the plan of schistosomiasis surveillance and consolidation anendment by collecting and analyzing the performance data of investment and effectiveness on schistosomiasis surveillance in the representative schistosomiasis transmission-interrupted areas from 2006 -20t0.Methods The historical endemic areas of Jiangshan and Fuyang counties of Zhejian Province,Qingxin and Sanshui counties of Guangdong Province, Fuqing and Longhai counties of Fujian Province were selected. The retrospective investigation,history review of the literature and field survey were performed to collect and analyze the data for input and effectiveness of schistosomiasis surveillance in the above six counties of the three provinces from 2006 to 2010.Results From 2006 to 2010,in the six counties of the three provinces,the rank of total financial input of funds and expenditure were as following:Jiangshan County,Zhejiang Province was the highest (824.60 ten thousand yuan investment,1 047.48 ten thousand yuan expenditures),Qingxing County,Guangdong Province was the minimum (14.50 ten thousand yuan investment,15.95 ten thousand yuan expenditures).Investment expenditure discounted analysis showed that in the six counties,in Guangdong Province,investment expenditure of two counties was low and also the relative value was small,compared with the other two provinces,both investment and expenditure,the absolute value difference was relatively large.In Zhejiang Province,the input and expenditure were balance in Fuyang County while high input and high expenses existed in Jiangshan County with both than the input expenditure much higher.In two counties of Fujian Province,investment and expenditure were from high to low and decreasing year by year.The results of schistosomiasis surveillance showed that the average positive rate of blood examination in population was 0.67％ in six counties of three provinces.Sanshui County of Guangdong Province was the highest ( 1.46％ ),whereas,Fuyang County of Zhejiang Province was the lowest (0.03％).The average egg positive rate was 1.04％ (4/383) among the positive poptdation after blood examination.Four imported confirmed cases were reported in Fuqing County of Fujian Province,The average egg positive rate was 7.02％ (4/57) mnong the positive population after blood examination.Moreover,the positive cases were not found by the method of stool examination in other counties.There were no positive cases upon examination of the total number of 6 811 bovines and 180 sheep in the above six counties.From 2006 to 2010,the total areas of snail investigation were 4 089.92 hm2 ( 1 hm2 =10 000 m2 ) and no positive snails were found after snails investigation in the six counties of the three provinces.Density of snails was 0.080 0 single/0.1m2 in Fuqing County,0.004 0single/ 0.1m2 in Longhai county of Fujian Province,0.001 0single/0.1m2 in Jiangshan County of Zhejiang Province respectively.No snails were found in the other three counties.The cover age rate of non-hazardous sanitary latrine was topped to 98.73％ in Sanshui County,Guangdong Province whereas 55.16％ was the lowest in Jiangshan County,Zhejiang Province in respect of manure management.Conclusion The measures of mainly surveillance on external source of infection supplemented with internal source of infection monitoring should be adopted in schistosomiasis transmission-interrupted areas while focusing on livestock screening from the endemic areas to improve the monitoring coverage.In the view of a large proportion of the investment-expenditure for snails survey and the wide areas investigation coverage,means of extending the cycle investigation andenvironmental improvement for monitoring the rotation should be taken.Since the low coverage rate of nonhazardous sanitary latrine in the part of counties,it needs to pay attention to the possibilities of potential source of infection.The results of schistosomiasis surveillance should be improved for the impact of lower investment in parts of counties.