Objective To study the diagnostic value of double-balloon endoscopy （ DBE ） and capsule endoscopy （CE） for small intestinal bleeding. Methods Overall detection rates of small intesti- nal bleeding with DBE, CE and the whole alimentary tract barium meal were compared. Positive rates of bleeding detection with DBE and CE were compared within the same patients. Influence of CE on one-procedure rate of DBE was analyzed. Results In 105 cases of small intestine bleeding, DBE detected 24 cases of Crohn＇s disease, 15 adenocarcinoma, 12 chronic nonspecific inflammation, 10 small intestinal ulcer of unknown reason, 8 entero-mesenchymoma, 8 polypus, 6 vascular deformation hemorrhage, 5 ancylosto- miasis, 5 Mechel＇s diverticula （ including multiple diverticula） , 3 lymphoma and 9 of no evident abnormalities. The positive detection rate of DBE is 91.4% （96/105）. Disease detection rates of CE and whole alimentary tract barium meal were 75.0% （30/40） and 33.3% （25/75） , respectively. The one-procedure rate of DBE is 90% （36/40） based on CE results, but it was only 69.2% （45/65） according to clinic features and the whole alimentary tract barium meal. Conclusion The main causes of small intestinal bleeding are benign ulcers （including Crohn＇s disease） and tumor, as well as chronic inflammation. Pol- yps, vascular deformation, parasitosis, Mechel＇s diverticulum and lymphoma are the secondary causes. DBE is superior to CE in diagnosis of small intestine bleeding, but CE can increase the one-procedure rate of DBE.