Review Article
Clinical advances of 18F-FDG PET/CT in evaluating differentiation of recurrent or metastatic differentiated thyroid cancer and guiding 131I therapy
Jiang Yongji, Huo Yanlei, Lyu Zhongwei, Ma Chao
Published 2022-09-25
Cite as Chin J Nucl Med Mol Imaging, 2022, 42(9): 559-562. DOI: 10.3760/cma.j.cn321828-20210413-00110
Abstract
Differentiated thyroid cancer (DTC) is prone to relapse and metastasize. In addition to thyroglobulin (Tg) and its antibodies, ultrasound and 131I whole-body scan (WBS), 18F-FDG PET/CT gains more use in the setting of recurrent or metastatic DTC and shows promise. This article mainly reviews the value of 18F-FDG PET/CT in the location of recurrent or metastasized DTC with negative 131I WBS but positive Tg (131I WBS-/Tg+ ), evaluating their differentiation, predicting the prognosis, guiding 131I treatment and its value in restaging DTC with moderate and high risk of relapse and guiding treatment decision.
Key words:
Thyroid neoplasms; Radiotherapy; Iodine radioisotopes; Positron-emission tomography; Tomography, X-ray computed; Fluorodeoxyglucose F18; Trends
Contributor Information
Jiang Yongji
Department of Nuclear Medicine, Tenth People′s Hospital of Tongji University, Shanghai 200072, China
Huo Yanlei
Department of Nuclear Medicine, Tenth People′s Hospital of Tongji University, Shanghai 200072, China
Lyu Zhongwei
Department of Nuclear Medicine, Tenth People′s Hospital of Tongji University, Shanghai 200072, China
Ma Chao
Department of Nuclear Medicine, Tenth People′s Hospital of Tongji University, Shanghai 200072, China