Clinical Research
Comparative study on memory monitoring between schizophrenia and obsessive-compulsive disorder
Hongchen Li, Chunyan Zhu, Yi Dong, Wen Xie, Xiaoqin Zhou, Huanzhong Liu, Yong Zhu, Yudan Luo
Published 2017-02-20
Cite as Chin J Behav Med & Brain Sci, 2017, 26(2): 118-122. DOI: 10.3760/cma.j.issn.1674-6554.2017.02.005
Abstract
ObjectiveTo compare the features of memory monitoring between schizophrenia and obsessive-compulsive disorder in patients.
Methods44 schizophrenia patients and 42 obsessive-compulsive disorder patients who met the DSM-V diagnosis and 51 healthy controls were assessed with feeling-of-knowing(FOK) for episode memory test.
ResultsSchizophrenia patients had significantly poorer cued recall and recognition performance (0.30(0.15, 0.50), 0.75(0.56, 0.90)) compared with healthy controls(0.70(0.50, 0.85), 0.95(0.85, 1.00)) and obsessive-compulsive disorder patients(0.65(0.39, 0.76), 0.95(0.84, 1.00))(all P<0.001). There was significant difference between obsessive-compulsive disorder patients and healthy controls in cued recall performance(P<0.05). There was no difference among the three groups in overestimate index(0.21(0.00, 0.32), 0.15(0.00, 0.33), 0.09(0.00, 0.25), all P>0.05). In underestimate index, schizophrenia patients’ values(0.12(0.00, 0.36)) were significantly higher than that of healthy controls(0.00(0.00, 0.22)) and obsessive-compulsive disorder patients(0.00(0.00, 0.20))(P<0.05, P<0.01), but there was no difference between obsessive-compulsive disorder patients and healthy controls(P>0.05). Schizophrenia patients’ Hamann index(0.19(-0.11, 0.43)) was significantly lower than that of healthy controls(0.56(0.14, 1.00)) and obsessive-compulsive disorder patients(0.41(0.13, 0.78))(P<0.01), but there was no difference between obsessive-compulsive disorder patients and healthy controls(P>0.05). Cued recall performance was positively correlated with Hamann index in patients with schizophrenia(r=0.39, P<0.01)and healthy controls(r=0.52, P<0.001).
ConclusionPatients with schizophrenia and obsessive-compulsive disorder both have episode memory impairments, memory monitoring impairment is observed in schizophrenia patients, but not in obsessive-compulsive disorder patients.
Key words:
Schizophrenia; Obsessive-compulsive disorder; Episodic memory; Memory monitoring; Feeling of knowing
Contributor Information
Hongchen Li
Department of Medical Psychology of Anhui Medical University, Hefei 230032, China
Chunyan Zhu
Department of Medical Psychology of Anhui Medical University, Hefei 230032, China
Yi Dong
Anhui Province Mental Health Center, Hefei 230032, China
Wen Xie
Anhui Province Mental Health Center, Hefei 230032, China
Xiaoqin Zhou
Anhui Province Mental Health Center, Hefei 230032, China
Huanzhong Liu
Anhui Province Mental Health Center, Hefei 230032, China
Yong Zhu
Department of Medical Psychology of Anhui Medical University, Hefei 230032, China
Yudan Luo
Department of Medical Psychology of Anhui Medical University, Hefei 230032, China
