Systematic Review
Cognitive dysfunction and event-related potentials in patients with chronic fatigue syndrome
Luo Tingting, Luo Yang, Tan Huijuan, Li Zimeng, Yuan Hongjie, Yang Lei, Jin Hongjiao, Zhu Xinyun, Wu Xi
Published 2017-10-20
Cite as Chin J Behav Med & Brain Sci, 2017,26(10): 955-960. DOI: 10.3760/cma.j.issn.1674-6554.2017.10.018
Abstract
Cognitive dysfunction, as a common symptom among patients with chronic fatigue syndrome(CFS) and patients with fibromyalgia(FM), impacts on life quality, occupation and study of these patients. However, the neural correlates to the cognitive impairment are unknown. Event related potentials, which reflect the information processing objectively and constantly, provide possibility for taking a insight into and estimating the dysfunction. By summarizing and analyzing studies in event related potentials about chronic fatigue syndrome, fibromyalgia, we found that CFS patients were characterized with prolonged latency of N200 and P300 accompanied by decreased P300 amplitude when they performed on Oddball paradigm, fibromyalgia patients were characterized with lower P300 amplitude when they concentrated on Oddball task, meanwhile, fibromyalgia patients also showed decreased P100/N100, P200, P300, LPC in emotional word decision task and somatic pictures decision task. It's suggests that the cognitive dysfunction in CFS is mainly caused by slowed speed of information identification and classification, whereas in FM it's dysregulation in attention control system results in the cognitive dysfunction. Limitations in current studies and prospects on researches about cognitive dysfunction in CFS for future were also discussed.
Key words:
Chronic fatigue syndrome; Fibromyalgia; Cognitive dysfunction; Event related potentials
Contributor Information
Luo Tingting
Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
Luo Yang
Clinical Medicine College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
Tan Huijuan
Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
Li Zimeng
Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
Yuan Hongjie
Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
Yang Lei
Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
Jin Hongjiao
Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
Zhu Xinyun
Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
Wu Xi
Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China