Clinical Research
Effects of oral-muscle biofeedback system training on rehabilitation of cognitive impairment in patients with obstructive sleep apnea after ischemic stroke
He Jun, Lu Tongbo, Zhu Jinmei, Qian Xue, Jiao Suqin, Yan Lixiang, Ding Yuquan, Zhang Lixia, Wang Tong
Published 2018-12-20
Cite as Chin J Behav Med & Brain Sci, 2018,27(12): 1100-1104. DOI: 10.3760/cma.j.issn.1674-6554.2018.12.009
Abstract
ObjectiveTo explore the effect of oral-muscle biofeedback system training on the rehabilitation of cognitive dysfunction in patients with obstructive sleep apnea (OSA) after ischemic stroke.
MethodsA total of 60 cases of poststroke OSA patients with cognitive dysfunction admitted to the rehabilitation center of deAn hospital in changzhou city from June 2017 to March 2018 were selected.On the basis of routine rehabilitation treatment, the control group was given positive pressure ventilation treatment, and the observation group was given oral muscle biofeedback system training.The changes of polysomnography (PSG) parameters, Montreal cognitive assessment(MoCA) score, serum matrix metalloproteinase-9 (MMP-9) and plasma homcysteinemia (Hcy) expression levels in the two groups before and after treatment were compared.
ResultsApnea hypopnea index and maximum apnea time of the two groups were significantly decreased after treatment compared with those before treatment, and the lowest SpO2 and average SpO2 were significantly higher than those before treatment(P<0.05). After treatment, MoCA total score and the dimensions score of patients in the observation group were significantly higher than those in the control group at the same time (P<0.05). After treatment, the levels of Hcy((12.38±4.54)μmol/L) and MMP-9((124.52±12.94)μg/L) in the observation group were significantly lower than those in the control group at the same time(Hcy(17.52±6.27)μmol/L, MMP-9(268.25±20.5 7)μg/L), and the difference was statistically significant (Hcy: t=3.637, P<0.05; MMP-9: t=32.395, P<0.05).
ConclusionsPositive pressure ventilation and oral muscle biofeedback system training have the same effect on OSA after stroke, but oral muscle biofeedback system training can also effectively improve patients' cognitive function.
Key words:
Oral muscle biofeedback system training; Stroke; Obstructive sleep apnea; Cognitive dysfunction
Contributor Information
He Jun
Rehabilitation Center of Changzhou Dean Hospital, Changzhou 213003, China
Lu Tongbo
Rehabilitation Center of Changzhou Dean Hospital, Changzhou 213003, China
Zhu Jinmei
Rehabilitation Center of Changzhou Dean Hospital, Changzhou 213003, China
Qian Xue
Rehabilitation Center of Changzhou Dean Hospital, Changzhou 213003, China
Jiao Suqin
Rehabilitation Center of Changzhou Dean Hospital, Changzhou 213003, China
Yan Lixiang
Rehabilitation Center of Changzhou Dean Hospital, Changzhou 213003, China
Ding Yuquan
Rehabilitation Center of Changzhou Dean Hospital, Changzhou 213003, China
Zhang Lixia
Rehabilitation Center of Jiangsu Provincial People's Hospital, Nanjing 210000, China
Wang Tong
Rehabilitation Center of Jiangsu Provincial People's Hospital, Nanjing 210000, China
