Section of New Application of Ultrasound in Tumor Ablation
Ultrasound-guided percutaneous transhepatic thrombolysis for treatment of portal vein thrombosis after liver transplantation
Jia Luo, Jianwei Lin, Liya Su, Manxia Lin, Wenzhe Fan, Xiaoyan Xie, Wenshuo Tian
Published 2017-06-20
Cite as , 2017, 19(6): 821-823. DOI: 10.3760/cma.j.issn.1008-1372.2017.06.007
Abstract
ObjectiveTo evaluate the effective and safety of ultrasound-guided percutaneous portal vein guide wire placement adjunct to thrombolytic catheter, which treating portal vein thrombosis after liver transplantation.
MethodsFrom Jan 2012 to Dec 2015, a total of 6 patients (5 male, 1 female, average age 50.6 years old, age range 41-65 years old ) with portal vein thrombosis after liver transplantation were retrospectively studied. The diagnosis was confirmed by contrast enhanced ultrasound (CEUS) with hypoechonic and no enhancement in portal vein. With ultrasound-guided a 18-guage guide wire was placed in right branch of portal vein, and a guidewire was placement. After exchanging the catheter, the thrombosis was confirmed again by venography. A thrombolytic catheter was placed and local thrombolysis therapy was performed.
ResultsThe guidewires were successfully placed in 6 patients. The thrombolytic catheters were successfully placed in 5 patients (day 2-60 after operation), and failed in 1 patient (9 years after operation). With 5-11 days urokinase injection, the patency of portal vein was found in 5 patients, of which 4 patients was treated by angioplasty and stent placement. With 16-31 months follow-up, the patency of portal vein was maintained. Neither server complication nor related-death was occurred.
ConclusionsUltrasound-guided percutaneous portal vein guide wire placement adjuncts thrombolytic catheter is effective and safety for treating portal vein thrombosis after liver transplantation.
Key words:
Ultrasonography; Portal vein/SU; Hepatic veins/SU; Phlebotomy; Thrombolytic therapy; Venous thromboembolism/CO/SU; Liver transplantation/AE
Contributor Information
Jia Luo
Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China
Jianwei Lin
The Organ Transplantation Center, the Third People's Hospital of Shenzhen, Shenzhen 518020, China
Liya Su
Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China
Manxia Lin
Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China
Wenzhe Fan
Department of Oncology Intervention, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China
Xiaoyan Xie
Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China
Wenshuo Tian
Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China