Objective To summarize the experience of treating 83 patients who have lntraspinal occupying lesions so as to give the effective treatment. Methods We confirmed 83 cases of intraspinal occupying lesions by CT or MRI examination, removed the lesion by using micro-surgery treatment, and observed the clinical recovery and long-term effect. Results 83 cases of intraspinal lesions were total treated with microsurgical surgery, without serious complications and death. Follow-up 1-5 years, except two cases of lumbodoral pain, one case of hydatid disease and one case of glioma relapse which were needed second operation, the remainders recovered well. Concllusions When the patients diagnosed with intraspinal occupying lesions they should conceive microsurgical treatment early and it can be lower operative damage, rapid recovery and satisfactory curative effect.