Objective To analyze the clinical efficacy of medicinal vesiculation for cough variant asthma in children.Methods 92 children that were hospitalized into our hospital from April,2010 to April,2012 and clinically diagnosed with cough variant asthma were select as study objects.According to different treatment methods,the patients were randomly divided into a control group taking placebo and a observation group receiving medicinal vesiculation therapy,46 cases for each group.The treatment efficacies were compared between the 2 groups.Results The treatment efficacy was better in the observation group than in the control group,with a statistical difference(97.83％ vs.89.13％,x2=2.947,P ＜ 0.05).Conclusions Medicinal vesiculation therapy for cough variant asthma in children can effectively improve their airway function and treatment effect.