Objective To study the influence of individualized health education in combination with repetitive transcranial magnetic stimulation on depression and anxiety in patients with Parkinson's disease and to provide some references for treating of Parkinson's disease.Methods 80 patients with Parkinson's disease complicated with anxiety and depression were selected from our hospital from April,2011 to June,2013 as study objects and were randomly divided into a control group and an observation group,40 cases for each group.The control group adopted repetitive transcranial magnetic stimulation intervention; in addition,the observation group received individualized health education.Depression self rating scale (SDS) and anxiety self rating scale (SAS) were used to assess the anxiety and depression of both groups' patients.The scores were analyzed and compared before and after treatment.Results After the treatment,SDS and SAS scores were improved in different degrees in both groups.3 weeks and 3 months after the treatment,the SDS scores were (49.1 ± 3.2) and (46.8 ± 1.8) and the SAS scores were (47.1 ± 3.3) and (46.3 ± 2.2) in the observation group and the SDS were (53.5 ± 3.1) and (52.6 ± 1.6) and the SAS scores were (49.7 ± 3.6) and (50.5 ± 3.7) in the control group,respectively,with statistical differences (P＜0.05).Conclusions Individualized health education in combination with repetitive transcranial magnetic stimulation for patients with Parkinson's disease is effective,can reduce the patients' depression and anxiety and improve their quality of life,has high clinical value,and is worth being generalized.