Treatises
Effect of tension-free repair of anterior peritoneal space on serum IL-17,IL-6 and IL-8 factor levels in patients with hernia
Dongsheng Shi, Pizhong Sun
Published 2019-05-15
Cite as IMHGN, 2019, 25(10): 1606-1608. DOI: 10.3760/cma.j.issn.1007-1245.2019.10.029
Abstract
ObjectiveTo investigate the effect of tension-free repair of anterior peritoneal space on the improvement of serum inflammatory factors in hernia patients.
Methods110 patients with hernia were selected from March 2017 to September 2018, and were randomly divided into a control group and an observation group, 55 cases for each group. The control group were treated with tension-free hernioplasty, and the observation group with tension-free repair of anterior peritoneal space. The serum levels of inflammatory factors, surgical parameters, and postoperative complications were compared between the two groups.
ResultsThe levels of IL-6, IL-8, and IL-17 as well as the intraoperative bleeding volume, operation time, time for off-bed activity after operation, wound pain duration, and hospitalization time were better in the observation group than in the control group [(9.07±1.08) pg/ml vs. (12.54 ±1.73) pg/ml, (23.49 ±7.58) pg/ml vs. (58.72 ±11.95) pg/ml, (44.29 ±11.68) pg/ml vs. (52.96 ±13.37) pg/ml, (26.94 ±6.15) ml vs. (45.23 ±8.07) ml, (35.72±6.19) min vs. (41.86±7.29) min, (2.79±0.86) h vs. (6.68 ±1.45) h, (1.31±0.48) d vs. (1.72±0.64) d, (5.06±0.83) d vs. (8.45±1.29) d, all P<0.05]. The incidence of postoperative complications was significantly lower in the observation group than in the control group [3.64% (2/55) vs. (20.00%) (11/55), P<0.05].
ConclusionTension free repair of anterior peritoneal space for hernia patients can reduce inflammation reaction, the incidence of postoperative complications, time for off-bed activity after operation, and pain duration, and is effective.
Key words:
Hernia; Tension-free repair anterior peritoneal space; Serum inflammatory factors; Complications
Contributor Information
Dongsheng Shi
Huangdao District Hospital of Traditional Chinese Medicine, Qingdao 266500, China
Pizhong Sun