Use of diagnostic vitrectomy in eyes with uveitis of unknown etiology
Lin Haiyan, Dai Rongping, Lin Yannan, Dong Fangtian, Zhang Meifen, Chen Youxin, Min Hanyi, Ye Junjie, Yu Weihong, Zhang Xiao
Published 2017-07-25
Cite as Chin J Ocul Fundus Dis, 2017,33(04): 404-406. DOI: 10.3760/cma.j.issn.1005-1015.2017.04.018
Abstract
ObjectiveTo analyze the results of diagnostic pars plana vitrectomy (PPV) in patients with uveitis of unknown cause.
MethodsThis is a retrospective case series study. Sixty-five patients (67 eyes) with uveitis of unknown cause were enrolled in this study. There were 31 males (32 eyes) and 34 females (35 eyes). The ages were from 6 to 84 years, with the mean age of (55.00±18.56) years. All eyes were received PPV. Examination of vitreous samples consisted of microbial stains and culture, microbial DNA and antibody detection, cytokine measurement, cytology, flow cytometry and gene rearrangement detection.
ResultsVitreous analysis was positive in 40 of 67 eyes (59.7%). Positive results indicated bacterial endophthalmitis in 20 of 40 eyes (50.0%), lymphoma in 11 eyes (27.5%), viral IgM and IgG increased significantly in 3 eyes (7.5%), fungal endophthalmitis in 3 eyes (7.5%), IgG of toxocara increased significantly in 2 eyes (5.0%), IgG of toxoplasma Gondii increased significantly in 1 eye (2.5%).
ConclusionThe diagnostic yield of vitreous samples in uveitis eyes of unknown cause is 59.7%.
Key words:
Uveitis/diagnosis; Endophthalmitis/diagnosis; Lymphoma/diagnosis; Vitrectomy
Contributor Information
Lin Haiyan
Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China (Lin Haiyan, now working at Department of Ophthalmology, The University of Hong Kong-Shenzhen Hospital)
Dai Rongping
Lin Yannan
Dong Fangtian
Zhang Meifen
Chen Youxin
Min Hanyi
Ye Junjie
Yu Weihong
Zhang Xiao
