指南与规范

中国肺癌筛查与早诊早治指南(2021,北京)

中华肿瘤杂志,2021, 43 (03): 243-268.

肺癌是中国发病率和死亡率最高的恶性肿瘤。筛查与早诊早治是降低人群肺癌死亡率的有效措施。制定符合中国国情的肺癌筛查与早诊早治指南,将极大推进中国肺癌筛查的同质性和优质性,提高肺癌筛查的效果。指南受国家卫生健康委员会疾病预防控制局委托与指导,由国家癌症中心发起,联合多学科专家共同制定。指南整合近年来国内外在肺癌筛查与早诊早治方面的新进展,同时考虑中国国情和肺癌筛查的实际经验,根据世界卫生组织指南制定手册的原则和方法,针对肺癌筛查过程中的筛查人群、技术、流程等给出了详细的循证推荐,旨在规范肺癌筛查与早诊早治实践,提升中国肺癌防控效果。

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一、引言

恶性肿瘤是威胁我国居民生命健康的重大慢性疾病。2015年中国肿瘤登记数据显示,我国恶性肿瘤新发病例约392.9万,死亡病例约233.8万[1]。恶性肿瘤负担呈现逐年上升趋势,防控形势日益严峻。而所有恶性肿瘤中,肺癌的发病率和死亡率均位居首位[1]。2000—2011年,中国男性和女性的肺癌发病与死亡总数均呈持续增高趋势[2]。GLOBOCAN 2020数据显示,中国肺癌发病数和死亡数分别占全球的37.0%和39.8%[3],肺癌防治是我国恶性肿瘤防控面临的重大挑战。

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贡献者信息

赫捷

国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院 100021

李霓

国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院 100021

陈万青

国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院 100021

吴宁

国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院 100021

沈洪兵

南京医科大学公共卫生学院 省部共建肿瘤个体化医学协同创新中心 211166

江宇

中国医学科学院北京协和医学院群医学及公共卫生学院 100730

李江

国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院 100021

王飞

国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院 100021

田金徽

兰州大学循证医学中心 730000

中国肺癌筛查与早诊早治指南制定顾问组

中国肺癌筛查与早诊早治指南制定专家组

中国肺癌筛查与早诊早治指南制定工作组

通信作者

赫捷

国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院 100021

Email:hejie@cicams.ac.cn

关键词

肺肿瘤;筛查;指南

利益冲突

利益冲突 所有作者声明不存在利益冲突

历史

出版日期:2021-03-23

收稿日期:2021-01-19

Guideline and Standard
China guideline for the screening and early detection of lung cancer(2021, Beijing)
He Jie,  Li Ni,  Chen Wanqing,  Wu Ning,  Shen Hongbing,  Jiang Yu,  Li Jiang,  Wang Fei,  Tian Jinhui,  Consulting Group of China Guideline for the Screening and Early Diagnosis and Treatment of Lung Cancer,  Expert Group of China Guideline for the Screening and Early Diagnosis and Treatment of Lung Cancer,  Working Group of China Guideline for the Screening and Early Diagnosis and Treatment of Lung Cancer
Published on 2021-03-23
Cite as Chin J Oncol, 2021,43(03): 243-268. DOI: 10.3760/cma.j.cn112152-20210119-00060
Abstract

In China, the malignant tumor with the highest incidence and motality is lung cancer (LC). As screening and early detection and treatment are effective in reducing LC mortality, formulating a guideline in line with China′s national conditions for the screening and early detection and treatment of LC will greatly promote the homogeneity and accuracy of LC screening, and result in an improvement of the effectiveness of LC screening. Commissioned and directed by the Disease Prevention and Control Bureau of the National Health Commission of the People′s Republic of China, the guidline was initiated by the National Cancer Center of China and formulated with joint effort by experts from different disciplines. Following the principles and methods in WHO Handbook for Guideline Development, the guidline integrates the latest development in LC screening and early diagnosis and treatment worldwide while fully considering China′s national conditions and practical experience in LC screening. It provides detailed evidence-based recommendations for different aspects of LC screening, such as the targeted population, the technologies and the procedures, to regulate the practices of LC screening and early diagnosis and treatment and enhance the effectiveness of the prevention and control of LC in China.

Key words:

Lung neoplasms; Screening; Guideline

Contributor Information
He Jie

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Li Ni

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Chen Wanqing

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Wu Ning

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Shen Hongbing

Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211166, China

Jiang Yu

School of Public Health and Population Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China

Li Jiang

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Wang Fei

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Tian Jinhui

Evidence Based Medicine Center of Lanzhou University, Lanzhou 730000, China

Consulting Group of China Guideline for the Screening and Early Diagnosis and Treatment of Lung Cancer
Expert Group of China Guideline for the Screening and Early Diagnosis and Treatment of Lung Cancer
Working Group of China Guideline for the Screening and Early Diagnosis and Treatment of Lung Cancer