To summarize the experience of clinical interventional therapy for post-thrombosis syndrome (PTS) and to explore the optimal timing and application principle.

From January 2010 to December 2017, 102 cases of lower extremity PTS who underwent interventional therapy were retrospectively reviewed. Of these, 49 had percutaneous transluminal angioplasty (PTA) alone (PTA group, mainly before 2014) and 53 had PTA plus implantation of stent (PTA+STENT group, of which 20 cases were implanted with trans-hip joint stent). Therapeutic effect was evaluated by using Villalta score, deep venous color Doppler ultrasonography and deep venography of the lower extremities during follow-up.

Technical success rates of both groups were 100%, respectively. The treatment frequency of PTA group was 2~3 times while PTA+STENT group was only once. Clinical symptoms such as edema and ulcer of the lower extremities of all patients were relieved gradually upon discharge. The Villalta score was improved as well, with a mean score of 8.76 in PTA group and 9.18 in PTA+STENT group (P<0.01) . The follow-up duration was 3~72 months, of which the follow-up rate was 100% (102 cases) in the time of 3~6 months while it decreased to 51.96% (53 cases) during the 6~72 month follow-up duration. Deep venous color Doppler ultrasonography and deep venography revealed iliac venous reocclusion in 23 cases, including 19 in PTA group with stent patency rate of 61.22% and 4 in PTA+STENT group with stent patency rate of 92.45% (P<0.01) .

PTA+STENT treatment of lower extremity deep vein thrombosis syndrome demonstrates a satisfactory mid-term clinical result, while the optimal treatment timing is related to the technical success rate and stent patency rate. However, the long-term patency of the stent needs further clinical observation.

Lower extremity deep vein thrombosis syndrome; Iliac vein occlusion; Vascular endovascular interventional; Stent