Group B Streptococcus (GBS) is one of the main pathogens causing neonatal infections in perinatal pregnant women, which can cause early invasive infections such as neonatal pneumonia, sepsis, meningitis, and even serious death. This article reviews the differences between the gold standard culture method, the rapid culture method and the real-time fluorescent quantitative polymerase chain reaction (PCR) method in the positive rate, sensitivity and specificity of maternal detection of GBS, and puts forward some suggestions for the detection methods used by pregnant women in different gestational weeks. This review suggested that screening and prevention of GBS nationwide will reduce maternal and child complications.

Group B streptococcus; Maternal; Culture method; Real-time fluorescence quantitative polymerase chain reaction technology