Cerebrovascular Disease
Correlation of aneurysm height/size ratio of blood vessel diameter and the risks of aneurysm rupture
Yongchun Chen, Weijian Chen, Shangchao Chen, Xianzhong Guo, Zequn Li, Bing Zhao, Yunjun Yang
Published 2016-07-28
Cite as Chin J Neurosurg, 2016, 32(7): 683-686. DOI: 10.3760/cma.j.issn.1001-2346.2016.07.008
Abstract
ObjectiveTo investigate the relationship between the maximum height of anterior communicating artery(AComA)aneurysm or the size ratio(SR)of mean diameter of peripheral blood vessels and aneurysm rupture.
MethodsThe morphological parameters of the aneurysms in 594 patients with AComA aneurysm admitted to the Department of Neurosurgery, the First Affiliated Hospital of Wenzhou Medical University from October 2010 to December 2014 were analyzed retrospectively. There were 529 patients with ruptured AcoA aneurysms and 65 with unruptured AComA aneurysms. The maximum height of aneurysms and the mean diameter of the peripheral vessels were collected respectively, and the relationship between SR and AComA aneurysm rupture in both of them were analyzed at the same time.
ResultsAmong the 594 patients with AComA aneurysm, the mean value of the maximum height of the aneurysms in the ruptured aneurysms was 4.26±2.19 mm. It was obviously larger than 2.82±2.04 mm of the unruptured aneurysms, and the mean diameter of the peripheral blood vessels of the ruptured aneurysms was 1.91±0.54 mm, it was smaller than the mean diameter of 2.16±0.49 mm in the peripheral blood vessels of the unruptured aneurysms. There was significant difference between both of them(all P<0.001). In the ruptured AComA aneurysms, the mean value of SR was 2.52±2.15, and that of the unruptured aneurysms was 1.38±1.09. There was significant difference between both of them(P<0.001). In addition, all the aneurysms were divided into 2 groups according to the size of the SR values. The rupture rate of aneurysms in the SR >2 group was significantly higher than that in the SR ≤2 group(P<0.001). After the analysis of ROC curve, the area under the curve of the SR ≤2 value of AComA aneurysms was 0.744, and the optimal cut-off value was 1.19.
ConclusionsThe size of SR value is significantly associated with the rupture of AComA aneurysms. When determining the treatment options for patients with AComA aneurysm in clinical practice, the SR value can be considered as a reference factor.
Key words:
Intracranial aneurysm; Anterior communicating artery; Rupture risk; Morphology
Contributor Information
Yongchun Chen
Department of Radiology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
Weijian Chen
Shangchao Chen
Xianzhong Guo
Zequn Li
Bing Zhao
Yunjun Yang
