Original Article
Early efficacy of three dimensional printed anatomical biomimetic cervical artificial disc replacement in the treatment of cervical degenerative diseases
Qian Lixiong, Yan Liang, Xu Zhengwei, Shan Lequn, Wang Wentao, He Limin, He Simin, Fan Yong, Ge Chaoyuan, Li Houkun, Hao Dingjun
Published 2022-03-01
Cite as Chin J Surg, 2022, 60(3): 223-229. DOI: 10.3760/cma.j.cn112139-20211202-00575
Abstract
ObjectiveTo investigate the efficacy and safety of a new cervical artificial disc prosthesis in the treatment of cervical degenerative diseases.
MethodsThe clinical data of 18 patients with single-level cervical degenerative diseases who underwent three dimensional printed anatomical bionic cervical disc replacement at Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University from May 2019 to July 2020 were analyzed retrospectively. There were 7 males and 11 females,aged (45±8) years old(range:28 to 58 years).The surgical segment was located at C3－4 level in 2 cases, C4－5 level in 5 cases, C5－6 level in 9 cases, and C6－7 level in 2 cases.The clinical and radiographic outcomes were recorded and compared at preoperative,postoperative times of one month and twelve months.The clinical assessments contained Japanese orthopedic association (JOA) score,neck disability index (NDI) and visual analogue scale (VAS).Imaging assessments included range of motion (ROM) of cervical spine, prosthesis subsidence and prosthesis anteroposterior migration.Repeated measurement variance analysis was used for comparison between groups,and paired t test was used for pairwise comparison.
ResultsAll patients underwent the operation successfully and were followed up for more than 12 months.Compared with preoperative score,the JOA score,NDI and VAS were significantly improved after surgery (all P<0.01).There was no significant difference in postoperative ROM compared with 1-and 12-month preoperative ROM (t=1.570,P=0.135;t=1.744,P=0.099). The prosthesis subsidence was (0.29±0.13) mm (range: 0.18 to 0.50 mm) at 12-month postoperatively.The migration of prosthesis at 12-months postoperatively were (0.71±0.20) mm (range: 0.44 to 1.08 mm).There was no prosthesis subsidence or migration>2 mm at 12-month postoperatively.
ConclusionThree dimensional printed anatomical biomimetic cervical artificial disc replacement has a good early clinical effect in the treatment of cervical degenerative diseases, good mobility can be obtained while maintaining stability.
Key words:
Cervical vertebrae; Bionics; Cervical artificial disc replacement; Three dimensional printed; Anatomical biomimetic
Contributor Information
Qian Lixiong
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
Yan Liang
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
Xu Zhengwei
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
Shan Lequn
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
Wang Wentao
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
He Limin
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
He Simin
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
Fan Yong
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
Ge Chaoyuan
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
Li Houkun
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
Hao Dingjun
Department of Spinal Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China
